CAS: 3614-47-9; 6-Hydrazinopyridazine-3-Carboxamide

该化合物是一种环球化合物,其核心为基,功能与氢基环和氨基氨基氨基甲酸酯混合物相同.这种结构具有独特的反应性,使其成为有机合成和制药研究的宝贵中间体. 氟二氮基乙烯组增强了其作为开发以氢区为基础的衍生物的构件的构件的潜力,而氨基氨的功能则有助于其溶解性和结合性.其定义明确的分子框架允许精确的修改,便利了药用化学的应用,特别是在酶抑制剂或生物活性剂的设计方面.该化合物的稳定性和合成多用途强调了其在研究和工业环境中的效用.

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    专利号:US-10925977-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
    发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
    权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
    摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

    专利号:KR-101513003-B1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy compositions and applications

    专利号:US-10814013-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:US-2008107598-A1
    优先权日:2006-10-05
    标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

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    1: Poulet J, Duclos H. [Value of the combination of a heterocyclic tertiary amine (pempidine) and a substituted hydralazine (hydracarbazine) in the ambulatory treatment of arterial hypertension]. Sem Ther. 1966 Oct;42(8):430-3. French.
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