CAS: 17733-22-1; 2-Chlorothioanisole

该化合物是一种有机化合物,其特点是既存在氯苯基化合物,也存在硫醇(mercaptan)功能组,其典型特征是无色的淡黄色液体,其大蒜或腐烂蛋的强烈,不愉快的气味可感性在硫柳树中十分常见;该化合物在有机溶剂中溶解,但由于其水分疏水特性,在水中溶性有限. 2 - Chlonobezyl Mercapton因其反应活动性而闻名,特别是在核分裂生物替代反应中,该物质组可形成解冻剂或与电极反应,在各种应用中使用,包括作为合成制药和农用化学物的中间体.此外,由于其强味,该化合物还可能在气体检测系统中用作警告剂.在处理该化合物时,安全防范措施至关重要,因为它可能会刺激皮肤,眼睛和呼吸系统.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号6320-03-2 2-氯苯硫酚 | CAS号74-88-4 碘甲烷 | CAS号95-50-1 邻二氯苯 | CAS号5188-07-8 甲硫醇钠 | CAS号74-93-1 甲硫醇 | CAS号15946-36-8 2-氯苯亚磺酸钠 | CAS号63451-08-1 2-chlorobenzene... | CAS号109418-89-5 (2-Chloro-4-(ch... | CAS号87776-75-8 3-氯-4-甲硫基苯乙酸 | CAS号89265-35-0 2-(甲基磺酰)苯磺酰氯化物 | CAS号60036-44-4 1,2-bis-methane... | CAS号6609-54-7 2-(甲基硫代)苯甲腈 | CAS号32467-66-6 1-(3-氯-4-(甲基硫代)苯基)乙酮 | CAS号172338-47-5 1-chloro-2-[(S)... | CAS号7321-57-5 1-CHLORO-2-(MET... | CAS号17482-05-2 2-氯苯基甲基砜

合成工艺路线路线简述

    邻氯苯硫酚 反应生成2-氯茴香硫醚
    参考文献:Dialysis-Resistant Pulmonary Oedema
    标题:Dialysis-Resistant Pulmonary Oedema
    摘要:
    Doi:10.1093/ndt/gfg136

    海关参考信息

    专利信息


    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-8367871-B2
    优先权日:2007-03-09
    标 题 :Process for production of optically active sulfoxide compound using iron-salan complex catalyst
    发明人:KATSUKI TSUTOMU; EGAMI HIROMICHI
    权利人:NISSAN CHEMICAL IND LTD; KATSUKI TSUTOMU; EGAMI HIROMICHI
    摘要:An optically active sulfoxide compound that is useful as an intermediate for synthesis or an active ingredient of a physiologically active substance such as a pharmaceutical agent is produced at a high optical purity. A process for producing an optically active sulfoxide compound of formula (4) comprises oxidizing a sulfide compound of formula (3) in the presence of an optically active metal complex of formula (1), (1′), (2) or (2′) by using an oxidizing agent. The present invention is also directed to the optically active metal complex.

    专利号:US-9676721-B2
    优先权日:2010-09-03
    标题 :Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:US-9555039-B2
    优先权日:2011-05-09
    标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

    专利号:CN-109135526-A
    优先权日:2018-07-20
    标 题 :A kind of synthesis technology of epoxidized soybean oil modified polyaspartate polyurea copolymer
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    主要参考文献

    [参考文献]: M Yoshida, Et Al. Analysis Of Chlorophenylmethylsulfides In The Urine Of Rats Injected With Chlorobenzene By High Performance Liquid Chromatography. Ind Health. 1985;23(4):283-7.

    合成参考文献


    摘要:Lattanzi, A., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 995.
    摘要:Katsuki, T., Science of Synthesis: Water in Organic Synthesis, (2012) 1, 60.
    摘要:Ouali, A.; Taillefer, M., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 2, 103.
    摘要:Grogan, G., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 303.
    摘要:Sokolovs, I.; Suna, E., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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