CAS: 17184-21-3; Cauloside A
该化合物是天然化合物,被归类为沙邦素,主要来源于卡洛普林二氯二苯并呋喃植物物种,其特点是其复杂的甘蓝素结构,通常由一种或多种糖糖糖相连的类固醇或丙烯丙酮组成.Caulouside A展示了各种生物活动,包括抗炎,抗氧化剂和潜在的抗癌特性,从而引起对药理研究的兴趣.它溶液在水中的溶解性有限,因为它具有疏水性,这是沙邦人常见的.此外,Caouluside A可能与细胞膜发生相互作用,影响膜的渗透性和细胞信号路径.该化合物在治疗应用中的安全情况和功效是不断调查的主题,突出其在草药和药物开发中作为生物活性剂的潜力.总体而言,Caulopide A是自然产品在健康和疾病中可以发挥的各种作用的一个令人着眼的引人入.
- 英文名称Cauloside A
- 中文名称葳岩仙皂苷 A
- IUPAC名称(4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
- 其它别名3β-(α-L-Arabinopyranosyloxy)-23-Hydroxy-5α-Olean-12-En-28-Oic Acid; 3β-(α-L-Arabinopyranosyloxy)-23-Hydroxyolean-12-En-28-Oic Acid; Hederagenin 3-O-α-L-Arabinoside; Prosapogenin Cp1; 3-(α-L-Arabinopyranosyloxy)-23-Hydroxyoleana-12-Ene-28-Oic Acid; Hederaginin 3-O-α-L-Arabinopyranoside; Beta2-Fatsin; Delta-Hederin
- CAS编号17184-21-3
- MFCD编号:MFCD26145181
- FDA UNII编号:QW2X5B5L5W
- 分子式:C35H56O8分子量:604.83
- 产品CID: 881358
- 产品分类天然产物 → 萜类
物理性质
上下游产品
diazomethane HN-saponin P hederagenin 28-O-3-O-α-L-arabinopyranosylhederagenin 28-O-β-D-glucopyranosyl-(1-6)-β-D-glucopyranoside hederagenin 3-O-β-D-xylopyranosyl-(1-2)-α-L-arabinopyranosidehedaragenin L-arabinose L-(+)-arabinose合成工艺路线路线简述
📜3-O-<β-D-Xylopyranosyl-(1-2)-α-L-Arabinopyranosyl>Hederagenin 28-O-<β-D-Glucopyranoside>置于水体系中,用 1,4-二氧六环 用作溶剂,化学反应 120.0H,反应生成葳岩仙皂苷 A
参考文献:Kim,Youn Chul; Higuchi,Ryuichi; Komori,Tetsuya,Liebigs Annalen Der Chemie,1992,# 5,P. 453-460
标题:Kim,Youn Chul; Higuchi,Ryuichi; Komori,Tetsuya,Liebigs Annalen Der Chemie,1992,# 5,P. 453-460
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Liu EW, Wang JL, Han LF, Chang YX, Wang T, Huo Y, Wang L, Gao XM. Pharmacokinetics study of asperosaponin VI and its metabolites cauloside A, HN saponin F and hederagenin. J Nat Med. 2014 Jul;68(3):488-97. doi: 10.1007/s11418-014-0821-4. Epub 2014 Mar 11. doi: 10.1021/np400758t. Epub 2013 Dec 11.
3: Njateng GS, Du Z, Gatsing D, Nanfack Donfack AR, Feussi Talla M, Kamdem Wabo H, Tane P, Mouokeu RS, Luo X, Kuiate JR. Antifungal properties of a new terpernoid saponin and other compounds from the stem bark of Polyscias fulva Hiern (Araliaceae). BMC Complement Altern Med. 2015 Feb 15;15:25. doi: 10.1186/s12906-015-0541-7.
4: Popov AM, Rovin IuG, Anisimov MM, Likhatskaia GN, Strigina LI. [Effect of triterpene glycosides on the stability of bilayer lipid membranes, containing different sterols]. Biofizika. 1982 Sep-Oct;27(5):827-31. Russian. doi: 10.1016/j.pestbp.2016.12.006. Epub 2016 Dec 18.
合成参考文献
参考文献:10.1248/bpb.25.472
摘要:Kim YK, Kim RG, Park SJ, Ha JH, Choi JW, Park HJ, Lee KT. In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells. Biol Pharm Bull. 2002 Apr;25(4):472–6. doi: 10.1248/bpb.25.472.
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