CAS: 85916-13-8; Di-Tert-Butyl 2,2'-Azanediyldiacetate

该化合物是有机合成的多用途中间体,特别因其在浸泡联结和手性辅助应用方面的作用而受到重视. 其叔丁基酯组在提供消毒保护,便利选择性反应的同时,提高了有机溶剂的溶性. 异丁基酯组是一个双功能连接器, 能够形成稳定的切酸盐或协调综合体. 该复合体在不对称合成和制药研究中非常有用, 因为它有能力引入具有高度对应选择性的手动中心. 它在温和的条件下稳定, 与一系列试剂相容性, 使得它成为复杂分子构造的实用选择. 建议在惰性大气下进行适当处理以保持再活动.

结构式图片

相似化合物

142-73-4 172317-17-8 66937-72-2

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号275371-57-8 di-tert-butyl (... | CAS号100-20-9 对苯二甲酰氯 | CAS号75-65-0 叔丁醇 | CAS号5292-43-3 溴乙酸叔丁酯 | CAS号58482-93-2 N-T-丁基甘氨酸 钠盐 | CAS号142-73-4 亚氨基二乙酸 | CAS号540-88-5 醋酸叔丁酯

合成工艺路线路线简述

  • 142-73-4 = 85916-13-8
    反应条件:1.1 Reagents: Perchloric Acid Solvents: Tert-Butanol,Tert-Butyl Acetate
    标题:Synthesis Of 4-(Phenylethynyl)-2,6-Bis[n,N-Bis(Carboxymethyl)Aminomethyl]Pyridine
    作者:Takalo,Harri; Et Al
    参考文献:Acta Chemica Scandinavica 日期:1988 卷标:42(6) 页码:373-7]

    275371-57-8 = 85916-13-8
    反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; 4 H,Rt
    标题:A New Generation Of Cross-Linkers For Selective Detection By Maldi Ms
    作者:Paramelle,David; Et Al
    参考文献:Proteomics 日期:2009 卷标:9(23) 页码:5384-5388]

    = 85916-13-8
    反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 3 H,45 °C2.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; 4 H,Rt
    标题:A New Generation Of Cross-Linkers For Selective Detection By Maldi Ms
    作者:Paramelle,David; Et Al
    参考文献:Proteomics 日期:2009 卷标:9(23) 页码:5384-5388
📜氯乙酸叔丁酯置于氨体系中,用 甲醇 作为反应溶剂,化学反应 7.0H,以95%的收率获得产物亚氨基二乙酸二叔丁酯
参考文献:亚氨基二乙酸二叔丁酯的制备方法
标题:亚氨基二乙酸二叔丁酯的制备方法
摘要:本发明公开了一种亚氨基二乙酸二叔丁酯的制备方法,用氨和氯乙酸叔丁酯为原料,包括以下步骤:于密闭条件下,使氨和氯乙酸叔丁酯在有机溶剂中反应,氨和氯乙酸叔丁酯的摩尔比为1:1~6,反应温度为10~65°C,反应压力为常压,反应时间为2~10H;反应结束后冷却至室温,过滤;滤液旋转蒸发除去有机溶剂后冷却至0°C,析出的固体为亚氨基二乙酸二叔丁酯.本发明所使用的溶剂无毒性,无污染,溶剂可以循环使用,本发明不使用任何催化剂和助催化剂,反应分离方法简单,产品亚氨基二乙酸二叔丁酯收率高.

海关参考信息

专利信息


专利号:US-8252778-B2
优先权日:2006-03-24
标题:Highly fluorinated oils and surfactants and methods of making and using same
发明人:YU YIHUA; JIANG ZHONG-XING
权利人:YU YIHUA; JIANG ZHONG-XING; UNIV UTAH RES FOUND
摘要:Disclosed are compounds comprising the structure: n nIn one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:WO-2023076938-A1
优先权日:2021-10-27
标题:Synthesis of restrained complexing agents

专利号:EP-1626982-B1
优先权日:2003-05-23
标 题:Metal chelate complexes immobilized on solid supports for peptide preparation
发明人:RYBKA ANDREAS; FRANK HANS-GEORG; BRACHT FRANZ-PETER; HABERL UDO
权利人:APLAGEN GMBH
摘要:Use of an activated solid phase and an anchoring part which is attached to a peptide for solid phase peptide synthesis, wherein the anchoring part is coordinatively and reversibly attached to the activated solid phase. nFurthermore provided is a process for competitively detachment of said anchoring part, for purification and refolding of said peptides. Provided are peptides with an anchoring part for coordinative and reversible attachment of said peptides to an activated solid phase.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: Yunpeng Ye, Et Al. Multivalent Carbocyanine Molecular Probes: Synthesis And Applications. Bioconjug Chem. 2005 Jan-Feb;16(1):51-61.

合成参考文献


参考文献:10.1023/a:1014543911596
摘要:Nazarenko AY, Robinson PD, Wilson RM, Kolchinski AG, Disch JS, Rybak-Akimova EV. Structural Consequences of Deacylation of Nickel(II) Cyclidenes in Acidic and Basic Conditions. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2002 Feb;42(1-2):83–8. doi: 10.1023/a:1014543911596.
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