2-Bromo-2-Methyl-Propionitrile置于硫酸体系中,化学反应生成 2-溴异丁酰胺 参考文献:Reaction Of N-Bromosuccinimide With Nitriles. Ii.2,3 Aliphatic Nitriles 标题:Reaction Of N-Bromosuccinimide With Nitriles. Ii.2,3 Aliphatic Nitriles 摘要: DOI:10.1021/jo01133A005
专利号:EP-0062322-A1 优先权日:1981-04-03 标 题 :Improved process for synthesis of hindered amine stabilizers for polymeric materials 发明人:LAI JOHN TA-YUAN 权利人:GOODRICH CO B F 摘要:Process for the synthesis of hindered polysubstituted α-amino acetamides by reaction of a secondary amine with an α-halo acetamide in a basic organic reaction medium and in the presence of a phase transfer catalyst. The product thus obtained can comprise a multifunctional compound having one or more hindered amino moieties. These compounds are highly effective as UV stabilizers in a variety of plastics, especially the alpha monoolefins.
专利号:US-4473694-A 优先权日:1981-04-03 标 题:Process for the preparation of polysubstituted α-aminoacetamides 发明人:LAI JOHN T 权利人:GOODRICH CO B F 摘要:Process for the synthesis of hindered polysubstituted alpha -amino acetamides which comprises first reacting an alpha -haloacetamide with a base to form an intermediate alpha -lactam which in turn is reacted with a primary or secondary amine. The product thus obtained can comprise a multifunctional compound having one or more hindered amino moieties. These compounds are highly effective as UV stabilizers in a variety of plastics, especially the alpha monoolefins.
专利号:US-2011091957-A1 优先权日:2005-09-13 标题:Protein-polymer conjugates and synthesis thereof 发明人:LELE BHALCHANDRA SHRIPAD; RUSSELL ALAN J 权利人:LELE BHALCHANDRA SHRIPAD; RUSSELL ALAN J 摘要:A method of synthesizing a protein-polymer conjugate includes the steps: covalently attaching at least one controlled radical polymerization initiator to a protein to form a protein-initiator composition; and mixing the protein-initiator composition with at least one monomer which undergoes controlled radical polymerization in the presence of the protein-initiator composition under conditions suitable to initiate the controlled radical polymerization.
专利号:CN-110746345-A 优先权日:2019-11-18 标 题:Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine
专利号:CN-110746345-B 优先权日:2019-11-18 标 题 :Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine
[参考文献]: Qian Chen, Et Al. Drug-Induced Self-Assembly Of Modified Albumins As Nano-Theranostics For Tumor-Targeted Combination Therapy. Acs Nano. 2015 May 26;9(5):5223-33.
合成参考文献
参考文献:10.1107/s1600536810026802 摘要:Haridharan N, Ramkumar V, Dhamodharan R. 2-Bromo-2-methyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide. Acta Crystallogr E Struct Rep Online. 2010 Jul 14;66(8):o2007. doi: 10.1107/s1600536810026802.