CAS: 677-43-0; N,N-Dimethylphosphoroamidic Dichloride

上下游产品

N,N-dimethylammonium chloride N,N,N',N'-Tetramethylphosphorodiamidic chloride dimethyl amine bis-(dimethylamino)methanedimefox N,N,N',N'-Tetramethylphosphorodiamidic chloride N,N-dimethyl-N',N''-diphenyl-phosphamideN,N-dimethyl-N',N''-diphenyl-phosphamide N,N-dimethyl-N',N'-diphenylphosphorodihydrazidic

📜N,N-Dimethylamidotetrachlorophosphorane置于二氧化硫体系中,用 乙醚 作为反应溶剂,以91.3%的收率获得产物n,N-二甲基磷氨基二氯化物
参考文献:Reaction Of 1,1-Dichloro-1-Nitrosobutane With N,N-Dimethylamidodichlorophosphite
标题:Reaction Of 1,1-Dichloro-1-Nitrosobutane With N,N-Dimethylamidodichlorophosphite
摘要:
DOI:10.1007/bf00957179

专利信息

专利号:US-12012427-B2
优先权日:2019-10-31
标 题 :Synthesis of Fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer
发明人：SINHA SURAJIT; KUNDU JAYANTA; GHOSH UJJWAL
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:Present invention relates to stable Fmoc protected Morpholino monomers and corresponding oligonucleotides (PMO) and efficient synthesis of the same involving chlorophosphoramidate and H-Phosphonate chemistry. Successful syntheses of the oligonucleotide with higher yield and lesser time have been accomplished employing solid phase synthesis and easy deprotection of Fmoc group with Piperidine.

专利号:US-8076476-B2
优先权日:2007-11-15
标 题 :Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits
发明人：REEVES MATTHEW DALE; WELLER DWIGHT D; LI YONGFU
权利人:REEVES MATTHEW DALE; WELLER DWIGHT D; LI YONGFU; AVI BIOPHARMA INC
摘要:Morpholino compounds are provided having the structure: n nwheren R 1 is selected from the group consisting of lower alkyl, di(lower alkyl)amino, and phenyl; R 2 is selected from the group consisting of lower alkyl, monocyclic arylmethyl, and monocyclic (aryloxy)methyl; R 3 is selected from the group consisting of triarylmethyl and hydrogen; and Y is selected from the group consisting of: a protected or unprotected hydroxyl or amino group; a chlorophosphoramidate group; and a phosphorodiamidate linkage to the ring nitrogen of a further morpholino compound or a morpholino oligomer. Such compounds include doubly protected morpholino guanine (MoG) monomers. Also described is their use in synthesis of morpholino oligomers.

专利号:US-2021130379-A1
优先权日:2019-10-31
标题 :Synthesis of fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer

专利号:WO-2009064471-A1
优先权日:2007-11-15
标 题:Method of synthesis of morpholino oligomers

专利号:CA-2704261-A1
优先权日:2007-11-15
标题:Method of synthesis of morpholino oligomers

专利号:US-2011098483-A1
优先权日:2008-03-27
标题 :Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof
发明人：PETASIS NICOS A; MYSLINSKA MALGORZATA
权利人:UNIV SOUTHERN CALIFORNIA
摘要:The invention relates to a nitrogen heterocycle compound of formula 1: n n n n n n n n n n Also disclosed are a method of synthesizing the compound and use of the compound for treating various diseases and conditions.