CAS: 6125-24-2; (2-Nitroethyl)Benzene

上下游产品

2-phenethyl iodide (2-nitroethenyl)benzene 1-phenyl-2-bromoethane nitrostyrene phenethylamine Methyl α-nitro-β-phenylpropionate 2-nitro-3-phenylpropan-1-ol 3-(2-Nitro-1-phenyl-ethyl)-cycloheptanone

📜β-硝基苯乙烯置于tri(1-Naphthyl)Phosphonium Tris(Pentafluorophenyl)Borohydride体系中,用 二氯甲烷-D2 作为反应溶剂,化学反应 12.0H,以100%的收率获得产物β-硝基苯乙烷
参考文献:沮丧的路易斯对(triarylphosphines / B(c 6 F 5)3)与michael受体反应的机理研究
标题:沮丧的路易斯对(triarylphosphines / B(c 6 F 5)3)与michael受体反应的机理研究
摘要:沮丧的路易斯对(flp)催化的michael受体还原是具有挑战性的反应,会随着特定的flp结构而发生.用亲电试剂报道了两个膦(ar 3 P),即三(1-萘基)膦和三(邻甲苯基)膦的反应动力学和平衡.flp(ar 3 P / B(c 6 F 5)3)未能在h 2压力下还原活化的烯烃的原因被证明是抑制还原反应的加氢磷酸化过程.根据mayr的自由线性能量关系,讨论了控制这两个途径的动力学和热力学因素.
DOI:10.1021/acs.Orglett.6B03868

专利信息

专利号:US-6248891-B1
优先权日:1997-05-23
标题:Synthesis of acridine derivative multidrug-resistant inhibitors
发明人：SHARP MATTHEW JUDE; MADER CATHERINE J; STRACHAN CALUM
权利人:GLAXO WELLCOME INC
摘要:Synthesis of the MDRI of formula (I) from intermediates of acridone acid of formula (II) and aminophenethyl isoquinoline of formula (III), via steps including coupling and conversion to yield the MDRI of formula (I).

专利号:US-2019078126-A1
优先权日:2017-09-08
标 题 :Polymerase-mediated, template-independent polynucleotide synthesis
发明人：BAIGA THOMAS; BURLEY MICHAEL ANDERSON; SMITH ALEXANDER
权利人:SIGMA ALDRICH CO LLC; MERCK PATENT GMBH
摘要:Methods for de novo synthesis of polynucleotides in which 3′-O-reversibly blocked nucleotides are attached to a solid support in the presence of an X family DNA polymerase and in the absence of a nucleic acid template.

专利号:US-9428524-B2
优先权日:2010-05-25
标 题:Synthetic process for the manufacture of ecteinascidin compounds
发明人：MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN
权利人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN; PHARMA MAR SA
摘要:This invention relates to compounds of formula II: wherein R 1 , R 2 , Prot SH , and Prot NH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.

专利号:WO-9955664-A1
优先权日:1998-04-24
标 题 :Preparation of carbocyclic compounds
发明人：BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
权利人:GILEAD SCIENCES INC; BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

专利号:US-6518438-B2
优先权日:1996-08-23
标题:Preparation of cyclohexene carboxylate derivatives
发明人：KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
权利人:GILEAD SCIENCES INC
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

专利号:US-5886213-A
优先权日:1997-08-22
标题:Preparation of carbocyclic compounds
发明人：KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
权利人:GILEAD SCIENCES INC
摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.