CAS: 57695-04-2; Sitamaquine,N,N-Diethyl-N'-(6-Methoxy-4-Methyl-Quinolin-8-yl)-Hexane-1,6-Diamine
- 英文名称Sitamaquine,N,N-Diethyl-N'-(6-Methoxy-4-Methyl-Quinolin-8-yl)-Hexane-1,6-Diamine
- 中文名称西罗莫斯
- IUPAC名称1,6-Hexanediamine, N,N-diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-
- 其它别名1,6-Hexanediamine,N,N-diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)- (9CI); 6-Methoxy-8-(6-diethylaminohexylamine)-4-methylquinoline; Sitamaquine
- CAS编号57695-04-2
- 分子式:C21H33N3O分子量:343.513
- 产品CID: 1551962
- 同类组份化合物CAS57695-04-2 (free base)1019640-33-5 (tosylate)5330-29-0 (2HCl)
- 产品分类有机原料 → 有机杂环化合物 → 喹啉及其衍生物
物理性质
MSDS等安全信息
- 警示词Danger
- 危险描述H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] - 防范说明P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P354+P338, P317, P321, P330, P333+P317, P362+P364, P405, and P501
上下游产品
6-甲氧基-4-甲基-喹啉-8-胺 8-Amino-6-Methoxy-4-Methylquinoline 57514-21-3合成工艺路线路线简述
📜6-甲氧基-4-甲基-喹啉-8-胺,6-溴-N,N-二乙基-1-己胺盐酸盐(1:1)置于乙醇,Sodium Acetate体系中,化学反应生成 西罗莫斯
参考文献:Campbell Et Al.,Journal Of The American Chemical Society,1946,Vol. 69,P. 1556,1559
标题:Campbell Et Al.,Journal Of The American Chemical Society,1946,Vol. 69,P. 1556,1559
海关参考信息
- 2905110000-甲醇
2933310010-吡啶
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Frampton JE. Tafenoquine: First Global Approval. Drugs. 2018 Sep;78(14):1517-1523. doi: 10.1007/s40265-018-0979-2. Review. doi: 10.1016/j.biopha.2014.08.009. Epub 2014 Aug 19. doi: 10.4269/ajtmh.2011.10-0409.
4: Vercesi AE, Docampo R. Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ. Biochem J. 1992 Jun 1;284 ( Pt 2):463-7.
5: Petty BG, Black JR, Hendrix CW, Lewis LD, Basiakos Y, Feinberg J, Pattison DG, Hafner R. Escalating multiple-dose safety and tolerance study of oral WR 6026 in HIV-infected subjects: AIDS clinical trials group 173. J Acquir Immune Defic Syndr. 1999 May 1;21(1):26-32. doi: 10.1186/s12936-017-2017-3. Review.
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