2-丙炔-1-醇 反应生成 丙炔氧基三甲基硅烷 参考文献:Synthesis Of Diosphenol Ethers By Means Of Alkoxytrimethylsilanes 标题:Synthesis Of Diosphenol Ethers By Means Of Alkoxytrimethylsilanes 摘要: DOI:10.1016/s0040-4039(00)85105-9
专利号:US-2007099915-A1 优先权日:2005-10-07 标题 :Inhibitors of the hiv integrase enzyme 发明人:DRESS KLAUS R; JOHNSON TED W; PLEWE MICHAEL B; TANIS STEVEN P; ZHU HUICHUN 权利人:PFIZER 摘要:The present invention is directed to compounds of formula (I), n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.
专利号:US-7468375-B2 优先权日:2004-04-26 标题:Inhibitors of the HIV integrase enzyme 发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU 权利人:PFIZER 摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.
专利号:EP-1873155-A1 优先权日:2004-04-26 标题:Inhibitors of the HIV integrase enzyme 发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; ZHU HUICHUN; ZHANG JUNHU 权利人:PFIZER 摘要:The present invention is directed to compounds of formula (I),n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus ('HIV') integrase enzyme.
专利号:SU-1735300-A1 优先权日:1990-01-22 标题 :Method for synthesis of s-trimethylsilyl esters of dithio- or tetrathiophosphoric acids
专利号:US-7692014-B2 优先权日:2004-04-26 标题:Inhibitors of the HIV integrase enzyme 发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; ZHU HUICHUN; ZHANG JUNHU 权利人:PFIZER 摘要:The present invention is directed to compounds of formula (I), n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.
专利号:US-6613942-B1 优先权日:1997-07-01 标题 :Glucagon antagonists/inverse agonists 发明人:LING ANTHONY; GREGOR VLAD; GONZALEZ JAVIER; HONG YUFENG; KIEL DAN; KUKI ATSUO; SHI SHENGHUA; NAERUM LARS; MADSEN PETER; SAMS CHRISTIAN; LAU JESPER; PLEWE MICHAEL BRUNO; FENG JUN; TENG MIN; JOHNSON MICHAEL DAVID; TESTON KIMBERLY ANN; SIDELMANN ULLA GROVE; KNUDSEN LOTTE BJERRE 权利人:NOVO NORDISK AS 摘要:Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof are disclosed. The compounds act to antagonize the action of the glucagon peptide hormone.