CAS: 53078-86-7; (αs,1α,4α)-α-Amino-1-Carboxy-4-Hydroxy-2,5-Cyclohexadiene-1-Propanoic Acid

专利信息

专利号:WO-2025031833-A1
优先权日:2023-08-04
标 题:Recombinant strain and use thereof in production of scoulerine
发明人：CHEN YUN; JIAO XIANG
权利人:CHRYSEA LTD; CHEN YUN
摘要:Disclosed are recombinant yeast strains and a use thereof in the production of a benzylisoquinoline alkaloid. The recombinant yeast strains comprise berberine bridge enzyme. De novo synthesis of scoulerine and a benzylisoquinoline alkaloid is achieved through multiple strategies, and the yield thereof is significantly increased. The recombinant yeast strains provided by the present invention can produce scoulerine and other benzylisoquinoline alkaloids at high efficiency, and has important value in applications.

专利号:US-2010317886-A1
优先权日:2009-06-11
标 题 :Synthesis of isotopically-labeled functionalized dienes
发明人：MARTINEZ RODOLFO A
权利人:MARTINEZ RODOLFO A
摘要:All labeled carbons are derived ultimately from CO, as carbon-13 is separated from its lighter isotope by cyrogenic distillation of carbon monoxide (CO). Creation of stereospecific and site-specific compounds used for starting materials will address growing demands for labeled compounds, including isotopically-labeled functionalized dienes. Functionalized diene compounds can be used as precursors for the production of isotopically labeled pharmaceuticals, biomolecules, and natural products.

专利号:US-2015317458-A1
优先权日:2012-12-06
标 题 :In silico prediction of enhanced nutrient content in plants by metabolic modelling
发明人：LOTZ KATRIN; LEPS MICHAEL; LEMKE RAINER; JUNKER BJOERN; SCHREIBER FALK
权利人:BASF PLANT SCIENCE CO GMBH
摘要:The present invention relates to a method for identifying at least one metabolic conversion step, the modulation of which increases the amount of a metabolite of interest in a plant cell, plant or plant part, said method comprising establishing a stoichiometric network model for the metabolism of the plant cell, plant or plant part including the synthesis pathway for the metabolite of interest, identifying at least one candidate metabolic conversion step by applying at least one algorithm of Growth-coupled Design, and validating the at least one candidate metabolic conversion step by a constraint-based modeling approach in the stoichiometric network model, wherein an increase in the metabolite of interest occurring in said constraint-based modeling approach is indicative for a metabolic conversion step, the modulation of which increases the amount of the metabolite of interest in the plant cell, plant or plant part. The present invention further relates to a method for generating a plant cell, plant or plant part which produces an increased amount of a metabolite of interest when compared to a control, said method comprising identifying a metabolic conversion step, the modulation of which increases a metabolite of interest in a plant cell, plant or plant part, by the method for identifying a metabolic conversion step and modulating the said metabolic conversion step such that the amount of the metabolite of interest is increased in vivo in a plant cell, plant or plant part.

专利号:US-2025115926-A1
优先权日:2023-10-05
标 题:Deregulated dhs and tyra enzymes of grasses enable efficient production of both tyrosine and phenylalanine
发明人：MAEDA HIROSHI; EL AZAZ JORGE
权利人:WISCONSIN ALUMNI RES FOUND
摘要:The present invention provides engineered cells and plants that express deregulated aromatic amino acid synthesis pathway enzymes from grasses. Methods for increasing the production of aromatic amino acids and their derivatives in cells and plants by engineering them to express these enzymes and methods for producing aromatic amino acids or derivatives thereof and/or sequestering carbon dioxide by growing the plants are also provided.

专利号:DE-3812158-A1
优先权日:1988-04-12
标 题 :METHOD FOR SYNTHESIS OF ORGANIC COMPOUNDS

专利号:US-7655777-B2
优先权日:1997-11-24
标题:Nucleic acid molecules associated with the tocopherol pathway
发明人：BHAT BARKUR G; BODDUPALLI SEKHAR S; KISHORE GANESH M; LIU JINGDONG; RANGWALA SHAUKAT H; VENKATRAMESH MYLAVARAPU
权利人:MONSANTO TECHNOLOGY LLC
摘要:The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and soybean associated with the tocopherol synthesis pathway enzymes. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.