CAS: 5034-68-4; (S)-4-(2-Amino-3-Hydroxypropyl)Phenol

该化合物是一种手性酚化合物,具有氨基和羟基功能组,使其成为有机合成和制药应用的多用途中间体,其立体特性(S)配置确保了高对称纯度,这对不对称合成和生物活性分子开发至关重要.反应组的存在允许选择性修改,使其能够用于制造复杂的分子,包括β-成虫离心体和其他药用活性化合物.该化合物在标准条件下的稳定性和极地溶剂溶解性进一步提高了其在研究和工业过程中的效用.其结构特性使得它对于研究酶相互作用和设计有针对性的治疗方法很有价值.

结构式图片

上下游产品

CAS号4089-07-0 L-酪氨酸乙酯盐酸盐 | CAS号1080-06-4 L-酪氨酸甲酯 | CAS号83345-46-4 B°C-L-酪氨醇 | CAS号3417-91-2 L-酪氨酸甲酯盐酸盐 | CAS号13512-31-7 Z-L-酪氨酸甲酯 | CAS号60-18-4 L-酪氨酸 | CAS号87745-27-5 L-酪氨醇盐酸盐 | CAS号20649-40-5 (E)-4-(3-羟基-1-丙... | CAS号187332-12-3 (S)-(-)-4-(4-羟基...

合成工艺路线路线简述

    📜L-酪氨酸置于palladium On Activated Charcoal N-甲基吗啉,Sodium Hydroxide,Sodium Tetrahydroborate,氢气体系中,用 四氢呋喃,甲醇,甲苯 作为反应溶剂,-15.0~20.0 °C,300.0 Kpa 条件下,反应 1.5H,反应生成 L-酪氨醇
    参考文献:Caplar,Vesna; Raza,Zlata; Katalenic,Darinka,Croatica Chemica Acta,2003,Vol. 76,# 1,P. 23-36
    标题:Caplar,Vesna; Raza,Zlata; Katalenic,Darinka,Croatica Chemica Acta,2003,Vol. 76,# 1,P. 23-36

    海关参考信息

    专利信息


    专利号:US-10040752-B2
    优先权日:2015-08-24
    标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
    发明人:MKRTCHYAN GNEL; YAO QINGWEI
    权利人:CODY LABORATORIES INC
    摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

    专利号:US-2001047100-A1
    优先权日:2000-04-26
    标 题:Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives
    发明人:KJAERSGAARD HANS JOERGEN; PHILLIPS JIM; ALI SYED M
    摘要:Novel intermediates useful in the preparation of optically active H 3 histamine receptor antagonist 2-(4-imidazoyl)-cyclopropyl derivatives are disclosed.

    专利号:US-2010143990-A1
    优先权日:2006-11-27
    标 题 :Fermentative production of hydroxytyrosol
    发明人:ACHKAR JUEHANE; FERRANDEZ ABEL
    权利人:ACHKAR JUEHANE; FERRANDEZ ABEL
    摘要:The present invention relates to a newly identified microorganisms capable of direct production of hydroxytyrosol (hereinafter also referred to as Hy-T) from a carbon source obtainable from the D-glucose metabolization pathway. The invention also relates to polynucleotide sequences comprising genes that encode proteins which are involved in the synthesis of Hy-T. The invention also relates to genetically engineered microorganisms and their use for the direct production of Hy-T.

    专利号:US-2014357576-A1
    优先权日:2013-05-31
    标题:Methods for enhancement of muscle protein synthesis
    发明人:BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
    权利人:NESTEC SA
    摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

    专利号:WO-2015040533-A1
    优先权日:2013-09-19
    标题:Methods for enhancing muscle protein synthesis during energy deficit
    发明人:BAILEY DAVID MARK; ZALTAS ERIC SCOTT; STELLINGWERFF TRENT; MOORE DANIEL RYAN; HAWLEY JOHN ALAN; BURKE LOUISE MARY
    权利人:PREMIER NUTRITION CORP
    摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis during periods of negative energy balance, or energy deficit. The methods include administering to an individual suffering from energy deficit a composition comprising protein in an amount from about 15 g to about 30 g during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof. The methods also include administering to an individual suffering from energy deficit a composition comprising protein during a time period selected from the group consisting of during exercise, post-exercise, and combinations thereof, wherein the protein is administered in a dose that is higher than doses typically recommended for individuals experiencing energy balance.

    专利号:US-2014294788-A1
    优先权日:2013-03-26
    标 题 :Methods for enhancing muscle protein synthesis following concurrent training
    发明人:BAILEY DAVID MARK; ZALTAS ERIC SCOTT; MOORE DANIEL RYAN; STELLINGWERFF TRENT
    权利人:NESTEC SA
    摘要:The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/j.bbrc.2003.12.140
    摘要:Hirota S, Suzuki M, Watanabe Y. Hydrophobic effect of trityrosine on heme ligand exchange during folding of cytochrome c. Biochemical and Biophysical Research Communications. 2004 Feb;314(2):452–8. doi: 10.1016/j.bbrc.2003.12.140.
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