CAS: 3398-16-1; 4-Bromo-3,5-Dimethylpyrazole

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CAS号67-51-6 3,5-二甲基吡唑 | CAS号51108-53-3 1-benzyl-4-brom... | CAS号130874-32-7 1-苯磺酰基-4-溴-3,5-... | CAS号84691-20-3 4,4-Dibromo-3,5... | CAS号30169-25-6 3,6-二(3,5-二甲基-1... | CAS号67940-38-9 difluoro-(3-bro... | CAS号64-17-5 乙醇 | CAS号32551-34-1 1,2,5-Oxadiazol... | CAS号270588-85-7 3,6-Bis(4-bromo... | CAS号934-48-5 3,5-二甲基吡唑-1-羰酰胺 | CAS号28188-06-9 1H-Pyrazole-1-c... | CAS号844891-04-9 1,3,5-三甲基-1H-吡唑... | CAS号847818-62-6 (1,3,5-三甲基-1H-吡... | CAS号130874-32-7 1-苯磺酰基-4-溴-3,5-... | CAS号15801-69-1 4-溴-1,3,5-三甲基吡唑

3,5-二甲基吡唑置于溴体系中,用 二氯甲烷 用作溶剂,化学反应生成3,5-二甲基-4-溴吡唑
参考文献:共轭胺加成中的有机催化.β-氨基酸衍生物的合成
标题:共轭胺加成中的有机催化.β-氨基酸衍生物的合成
摘要:当手性硫脲用作活化剂时,O-保护的羟胺与吡唑衍生的烯酸酯的共轭加成以高效率和对映选择性进行.多种底物经历共轭胺加成,提供对映体富集的 β-氨基酸衍生物的途径.已经确定了最佳硫脲催化剂的结构要求,结果表明它可以作为双功能催化剂运行.
Doi:10.1021/ja071739C

专利信息

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-9428502-B2
优先权日:2012-07-03
标题:Heterocyclic modulators of lipid synthesis
发明人：OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; WAGMAN ALLAN S
权利人:3-V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.

专利号:US-2018222892-A1
优先权日:2012-07-03
标 题 :Heterocyclic modulators of lipid synthesis

专利号:EP-3083583-B1
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof

专利号:EP-3083583-A1
优先权日:2013-12-20
标题 :Heterocyclic modulators of lipid synthesis and combinations thereof

专利号:US-10053450-B2
优先权日:2012-07-03
标题 :Heterocyclic modulators of lipid synthesis