CAS: 20577-27-9; 2-Oxo-1,2-Dihydropyridine-3-Carbonitrile

相似化合物

609-71-2 94805-52-4 1003-56-1

上下游产品

CAS号6602-54-6 2-氯烟腈 | CAS号14906-64-0 3-氰基吡啶氮氧化物 | CAS号102-52-3 1,1,3,3-四甲氧基丙烷 | CAS号107-91-5 氰乙酰胺 | CAS号1986-81-8 烟碱-N-氧化物 | CAS号122-31-6 1,1,3,3-四乙氧基丙烷 | CAS号110-89-4 六氢吡啶 | CAS号5444-80-4 1,3,3-Triethoxy... | CAS号405224-22-8 5-溴-3-氰基-2(1H)-吡啶酮 | CAS号405224-24-0 5-溴-1H-吡唑并[3,4-... | CAS号405224-23-9 5-溴-2-氯烟腈 | CAS号27805-12-5 Ethyl 2-hydroxy... | CAS号85468-38-8 3-氨甲基吡啶-2-酮盐酸盐 | CAS号609-71-2 2-羟基烟酸 | CAS号766515-33-7 5-碘-2-氧代-1,2-二氢... | CAS号766515-34-8 2-氯-3-氰基-5-碘吡啶 | CAS号10128-92-4 3-Pyridinecarbo... | CAS号766515-35-9 1-甲基-3-氨基-5-碘吡啶并咪唑

N-氧代烟酰胺置于乙酸酐体系中,化学反应 12.0H,反应生成2-羟基-3-氰基吡啶
参考文献:Nagano,Hiroyuki; Nawata,Yoshiharu; Hamana,Masatomo,Chemical And Pharmaceutical Bulletin,1987,Vol. 35,# 10,P. 4068-4077
标题:Nagano,Hiroyuki; Nawata,Yoshiharu; Hamana,Masatomo,Chemical And Pharmaceutical Bulletin,1987,Vol. 35,# 10,P. 4068-4077

专利信息

专利号:US-3666765-A
优先权日:1969-10-27
标 题:Synthesis of 2-pyridones and derivatives thereof
发明人：BERIJCKERE ANTOON M; ELOY FERNAND G F
权利人:UNION CARBIDE CORP
摘要:2-Pyridones are conveniently synthesized from 2,4-pentadienoic acids by formation of the acid azide, decomposition of the azide into an isocyanate and the simultaneous cyclization of the isocyanate into the pyridone. The pyridones are readily converted into known pyridines.

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:WO-9321213-A1
优先权日:1992-04-16
标题 :Alpha-aminoboronic acid peptides and their use as elastase inhibitors
发明人：BERNSTEIN PETER ROBERT; SHAW ANDREW; SHENVI ASHOKKUMAR BHIKKAPPA; THOMAS ROYSTON MARTIN; WARNER PETER; WOLANIN DONALD JOHN
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic derivatives which are 1-pyridylacetamide derivatives of formula (I), set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases on mammals in which (HLE) is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic derivatives, processes for preparing the heterocyclic derivatives, pharmaceutical compositions containing such heterocyclic derivatives and methods for their use.

专利号:US-5721222-A
优先权日:1992-04-16
标 题 :Heterocyclic ketones
发明人：BERNSTEIN PETER ROBERT; SHAW ANDREW; THOMAS ROYSTON MARTIN; VEALE CHRIS ALLAN; WARNER PETER; WOLANIN DONALD JOHN
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic ketones which are 1-pyridylacetamide ketones of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic ketones, processes for preparing the heterocyclic ketones, pharmaceutical compositions containing such heterocyclic ketones and methods for their use.

专利号:FR-2686340-A1
优先权日:1992-01-22
标题:PROCESS FOR THE SYNTHESIS OF CARBOXYLIC PYRIDINES OR ORTHOHALOGENATED CARBOXAMIDES AND NOVEL CARBOXYLIC PYRIDINES OR ORTHOFLUOROUS CARBOXAMIDES.

专利号:US-5521179-A
优先权日:1991-04-18
标题 :Heterocyclic amides
发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.