CAS: 928-92-7; (E)-Hex-4-En-1-Ol

• 英文名称(E)-Hex-4-En-1-Ol
• 中文名称(4E)-4-己烯-1-醇
• IUPAC名称(E)-hex-4-en-1-ol
• 其它别名(E)-4-己烯-1-醇; 4-Hexen-1-Ol
• CAS编号928-92-7
• MFCD编号:MFCD00009713
• EINECS号:213-188-6
• 分子式:C6H12O分子量:100.16
• 产品CID: 1967680
• 产品分类有机原料→分子砌块→脂肪链类化合物

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: VTIODUHBZHNXFP-NSCUHMNNSA-N
• InChI=1S/C6H12O/c1-2-3-4-5-6-7/h2-3,7H,4-6H2,1H3/b3-2+
• 计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数3.0

相似化合物

物理性质

• 熔点22.55 °C
• 沸点159-160 °C at 760 mmHg
• 闪点61.1±0.0 °C
• 密度0.8±0.1 g/cm3
• pKa:15.13±0.10(预测)
• PSA:20.23
• LogP:1.9711
• 折射率1.443
• 蒸汽压0.9±0.6 mmHg at 25°C
• 溶解性Chloroform, Methanol (Slightly)
• 敏感性常温常压下稳定
• 外观形态无色液体
• 储存条件冰箱, 置于惰性气氛下
• 产品应用该化合物用作食物调味剂; 口味配方中使用的个别调味成分不得超过2760GB中规定的最大允许使用量和残留量.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别严重眼刺激 类别2
  严重眼刺激 类别2A
  易燃液体 类别4
• 警示词Warning(警告)
• 危险描述H319 |造成严重眼刺激.
  H227 |可燃液体
• 防范说明P210-P264-P280-P370+P378-P403-P501
• 危险等级3.2
• UN编号1993
• 危险品标志Xi
• 包装等级III
• 安全声明26
• 危险类别码36
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 (E)-4-Hexen-1-Ol 主要起始原料 5-Hexen-1-Ol
• 821-41-0 = 928-92-7
  反应条件:1.1 Reagents: (Ethenyloxy)Trimethylsilane Catalysts: (Sp-5-41)-Dichloro[1,3-Dihydro-1,3-Bis(2,4,6-Trimethylphenyl)-2H-Imidazol-2-Ylid... Solvents: Dichloromethane; 3 H,50 °C
  标题:Selective Isomerization Of A Terminal Olefin Catalyzed By A Ruthenium Complex: The Synthesis Of Indoles Through Ring-Closing Metathesis
  作者:Arisawa,Mitsuhiro; Terada,Yukiyoshi; Nakagawa,Masako; Nishida,Atsushi
  参考文献:Angewandte Chemie 日期:2002 卷标:41(24) 页码:4732-4734]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Diethyl Ether; 0 °C; 0 °C -> Rt; 3 H,Rt1.2 Reagents: Water1.3 Reagents: Sodium Hydroxide Solvents: Water
  标题:Total Synthesis Of (-)-Histrionicotoxin
  作者:Adachi,Yohei; Kamei,Noriyuki; Yokoshima,Satoshi; Fukuyama,Tohru
  参考文献:Organic Letters 日期:2011 卷标:13(16) 页码:4446-4449]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Diethyl Ether; 0 °C; 90 Min,0 °C1.2 Solvents: Ethyl Acetate1.3 Reagents: Water1.4 Reagents: Sodium Hydroxide Solvents: Water
  标题:Capturing Primary Ozonides For A Syn-Dihydroxylation Of Olefins
  作者:Arriaga,Danniel K.; Thomas,Andy A.
  参考文献:Nature Chemistry 日期:2023 卷标:15(9) 页码:1262-1266]
  
  55230-25-6 = 928-92-7
  反应条件:1.1 Reagents: Sodium Solvents: Ammonia
  标题:Stereoselective Synthesis Of Alkenyl Alcohols Using Dissolving Metal (Calcium,Sodium) Reduction
  作者:Zhou,Jingyao; Lu,Guodi; Huang,Xin; Wu,Shihui
  参考文献:Synthetic Communications 日期:1991 卷标:21(3) 页码:435-41]
  
  72081-15-3 = 928-92-7
  反应条件:1.1 Reagents: Methyllithium Catalysts: Cuprous Cyanide Solvents: Diethyl Ether,Pentane1.2 Reagents: Water
  标题:A Stereoselective Synthesis Of Functionalized Alkenyllithiums And Alkenyl Cyanocuprates By The Copper(I)-Catalyzed Coupling Of Organolithium Reagents With α-Lithiated Cyclic Enol Ethers
  作者:Kocienski,Philip; Wadman,Sjoerd; Cooper,Kelvin
  参考文献:Journal Of The American Chemical Society 日期:1989 卷标:111(6) 页码:2363-5]
  
  31535-05-4 = 928-92-7
  反应条件:1.1 Reagents: Sodium
  标题:3,4-Dihydro-2H-Pyran
  作者:Kierkus,Paul Ch.
  参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2001 卷标:1 页码:1-4]
  
  2430-27-5 = 928-92-7
  反应条件:1.1 Reagents: Sodium Bicarbonate,Oxygen Solvents: Acetone,Ethyl Acetate; 40 Min,Rt; 1 H
  标题:Characterization Of An Epoxide Hydrolase From The Florida Red Tide Dinoflagellate,Karenia Brevis
  作者:Sun,Pengfei; Leeson,Cristian; Zhi,Xiaoduo; Leng,Fenfei; Pierce,Richard H.; Et Al
  参考文献:Phytochemistry (Elsevier) 日期:2016 卷标:122 页码:11-21]
  
  821-41-0 = 928-92-7
  反应条件:1.1 Reagents: (Ethenyloxy)Trimethylsilane Catalysts: Grubbs Second Generation Catalyst Solvents: Dichloromethane; 1.5 H,Reflux
  标题:Development Of Isomerization And Cycloisomerization With Use Of A Ruthenium Hydride With N-Heterocyclic Carbene And Its Application To The Synthesis Of Heterocycles
  作者:Arisawa,Mitsuhiro; Terada,Yukiyoshi; Takahashi,Kazuyuki; Nakagawa,Masako; Nishida,Atsushi
  参考文献:Journal Of Organic Chemistry 日期:2006 卷标:71(11) 页码:4255-4261]
  
  31535-05-4 = 928-92-7
  反应条件:1.1 Reagents: Sodium Solvents: Diethyl Ether,P-Xylene
  标题:Synthesis Of (+/-)-Brevioxime And (+/-)-Puraquinonic Acid And Studies On Peptide Ligation And Acyl Transfer
  作者:Hisaindee,Soleiman
  参考文献:2003 卷标:64(7)]
  
  53107-05-4 = 928-92-7
  反应条件:1.1 Reagents: Magnesium Solvents: Diethyl Ether
  标题:Magnesium Ring Scission Reaction Of 2-Alkyl-3-Chlorotetrahydropyran
  作者:Ding,Xinteng; Ge,Yu; Teng,Zhu; Fan,Junyao
  参考文献:Huaxue Xuebao 日期:1987 卷标:45(11) 页码:1138-9]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran
  标题:Iron-Catalyzed Intramolecular Allylic C-H Amination
  作者:Paradine,Shauna M.; White,M. Christina
  参考文献:Journal Of The American Chemical Society 日期:2012 卷标:134(4) 页码:2036-2039]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Diethyl Ether
  标题:Catalytic Epoxidation Of Alkenes With Oxone
  作者:Denmark,Scott E.; Forbes,David C.; Hays,David S.; Depue,Jeffrey S.; Wilde,Richard G.
  参考文献:Journal Of Organic Chemistry 日期:1995 卷标:60(5) 页码:1391-407]
  
  110-87-2 = 928-92-7
  反应条件:1.1 Reagents: Sodium,Chlorine Solvents: Diethyl Ether
  标题:(E)-4-Hexen-1-Ol
  作者:Paul,Raymond; Riobe,Olivier; Maumy,Michel
  参考文献:Organic Syntheses 日期:1976 卷标:55 页码:62-7]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tert-Butyl Methyl Ether; Overnight,Rt1.2 Reagents: Sulfuric Acid Solvents: Water
  标题:Iodide-Catalyzed Cyclization Of Unsaturated N-Chloroamines: A New Way To Synthesize 3-Chloropiperidines
  作者:Noack,Michael; Gottlich,Richard
  参考文献:European Journal Of Organic Chemistry 日期:2002 卷标:(18) 页码:3171-3178]
  
  156051-16-0 = 928-92-7
  反应条件:1.1 Reagents: Sodium Solvents: Diisopropyl Ether
  标题:The Synthesis Of Some 4-Alken-1-Ols
  作者:Brandon,Richard C.; Derfer,John M.; Boord,Cecil E.
  参考文献:Journal Of The American Chemical Society 日期:1950 卷标:72 页码:2120-2]
  
  34495-74-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 30 Min,0 °C; 0 °C -> Rt; 5 Min,Rt1.2 Reagents: Sodium Sulfate Solvents: Water; 0 °C
  标题:Total Synthesis And Biological Evaluation Of Siladenoserinol A And Its Analogues
  作者:Yoshida,Masahito; Saito,Koya; Kato,Hikaru; Tsukamoto,Sachiko; Doi,Takayuki
  参考文献:Angewandte Chemie 日期:2018 卷标:57(18) 页码:5147-5150]
  
  5371-52-8 + 4736-60-1 = 928-92-7
  反应条件:1.1 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; -78 °C
  标题:Highly Functionalized And Potent Antiviral Cyclopentane Derivatives Formed By A Tandem Process Consisting Of Organometallic,Transition-Metal-Catalyzed,And Radical Reaction Steps
  作者:Jagtap,Pratap R.; Ford,Leigh; Deister,Elmar; Pohl,Radek; Cisarova,Ivana; Et Al
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(33) 页码:10298-10304]
  
  917-54-4 + 110-87-2 = 928-92-7 [标题:Reaction Conditions
  标题:Preparation And Application Of Thermo-Color Materials Based On Heat Sensitive Dyestuffs
  作者:Guo,Jiazhen; Cheng,Qichao; Liu,Zhengtang
  参考文献:Huagong Jinzhan 日期:1997 卷标:(6) 页码:57-59]
  
  25166-87-4 = 928-92-7
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Diethyl Ether
  标题:Intramolecular N-Alkenylnitrone Additions. Regio- And Stereochemistry
  作者:Oppolzer,W.; Siles,S.; Snowden,R. L.; Bakker,B. H.; Petrzilka,M.
  参考文献:Tetrahedron 日期:1985 卷标:41(17) 页码:3497-509

海关参考信息

• 2901210000-乙烯
  2901220000-丙烯
  2905121000-正丙醇
  2905130000-正丁醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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• ➥ 象形图和危险代码
• ➥ 防范代码详解
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