CAS: 81907-61-1; (2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-Dihydroxy-4,4,10,13,14-Pentamethyl-11,15-Dioxo-2,3,5,6,7,12,16,17-Octahydro-1H-Cyclopenta[a]Phenanthren-17-Yl]-2-Methyl-4-Oxoheptanoic Acid

该化合物是一种主要来自Ganoderma learningum蘑菇(通常称为Reishi或Lingzhi)的三叶类化合物,其特点是复杂的分子结构,包括多环和功能组,有助于其生物活性;甘代尔酸B具有各种药理特性,包括抗炎,抗氧化剂和潜在的抗癌影响,使其对药用化学和天然产品研究感兴趣;通常见于甘代尔马物种的果实体和菌类中,并经常研究其在传统医药和潜在治疗用途中的作用;该化合物在有机溶剂中溶解,但水溶性有限,影响生物系统的生物利用和功效;研究继续探索其行动机制和潜在健康惠益,突出天然化合物在......

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    参考文献:10.1615/intjmedmushrooms.v1.i2.40
    摘要:Chen R, Yu D. Studies on the Triterpenoid Constituents of the Spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae). Int J Med Mushrooms. 1999;1(2):147–52. doi: 10.1615/intjmedmushrooms.v1.i2.40.
    参考文献:10.1248/cpb.33.4829
    摘要:KOMODA Y, NAKAMURA H, ISHIHARA S, UCHIDA M, KOHDA H, YAMASAKI K. Structures of new terpenoid constituents of Ganoderma lucidum (Fr.) KARST (Polyporaceae). Chem. Pharm. Bull. 1985;33(11):4829–35. doi: 10.1248/cpb.33.4829.
    参考文献:10.1016/j.bmcl.2010.06.093
    摘要:Lee I, Kim J, Ryoo I, Kim Y, Choo S, Yoo I, Min B, Na M, Hattori M, Bae K. Lanostane triterpenes from Ganoderma lucidum suppress the adipogenesis in 3T3-L1 cells through down-regulation of SREBP-1c. Bioorganic & Medicinal Chemistry Letters. 2010 Sep;20(18):5577–81. doi: 10.1016/j.bmcl.2010.06.093.
    参考文献:10.1615/intjmedmushrooms.v19.i5.70
    摘要:Ramakrishna M, Babu DR, Veena SS, Pandey M, Rao N. A Validated Reverse-Phase HPLC Method for Quantitative Determination of Ganoderic Acids A and B in Cultivated Strains of Ganoderma spp. (Agaricomycetes) Indigenous to India. Int J Med Mushrooms. 2017;19(5):457–65. doi: 10.1615/intjmedmushrooms.v19.i5.70.
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