CAS: 6795-60-4; (8R,9S,10R,13S,14S,17R)-17-Ethenyl-17-Hydroxy-13-Methyl-1,2,6,7,8,9,10,11,12,14,15,16-Dodecahydrocyclopenta[a]Phenanthren-3-One
该化合物是合成蛋白质,一种类类固醇激素,模仿体内的蛋白质作用,其特征是与其他类固醇激素结构相似,具有环球热量,具有环球性激素,具有氢酚固酯核心,诺维尼斯特酮主要用于荷尔蒙避孕药,并可用于治疗各种月经紊乱,其行动机制对孕素受体具有约束力,导致腹腔衬衬内改变和抑制排卵.该物质通常以口服形式施用,以相对较高的威力和效力著称.此外,诺维尼斯特酮具有一系列的药理效应,包括抗和诱发性特性,对许多合成激素可能有副作用,其使用应当由保健专业人员加以监测.
- 英文名称(8R,9S,10R,13S,14S,17R)-17-Ethenyl-17-Hydroxy-13-Methyl-1,2,6,7,8,9,10,11,12,14,15,16-Dodecahydrocyclopenta[a]Phenanthren-3-One
- 中文名称诺乙烯酮
- IUPAC名称17beta-Hydroxy-17alpha-vinylestr-4-en-3-one
- 其它别名19-Nor-17a-pregna-4,20-dien-3-one,17-hydroxy- (6CI,7CI,8CI); 17a-Vinyl-17b-hydroxy-D4-estren-3-one; 17a-Vinyl-19-nortestosterone; 17b-Hydroxy-17a-vinylestr-4-en-3-one; 19-Nortestosterone, 17-ethenyl-; Neoprogestin; Nor-progestelea; Norvinisterone
- CAS编号6795-60-4
- MFCD编号:MFCD00868446
- FDA UNII编号:7Q843V12Q0
- 分子式:C20H28O2分子量:300.44
- 产品CID: 1665588
- 产品分类有机原料 → 脂质和类脂质分子 → 类固醇和类固醇衍生物
物理性质
MSDS等安全信息
上下游产品
炔诺酮 Norethisterone 68-22-43-Methoxy-19-Nor-17βh-Pregna-2,5(10)-Dien-20-Yn-17-Ol 19357-36-9
合成工艺路线路线简述
📜炔诺酮置于吡啶,Lindlar'S Catalyst体系中,化学反应生成 诺乙烯酮
参考文献:17-(Beta-Hydroxyethylidene)-13-Methyl-1,2,3,6,7,8,9,10,11,12,13,14,16,17-Tetradecahydro-15H-Cyclopenta [a] Phenanthren-3-One And Esters Thereof
标题:17-(Beta-Hydroxyethylidene)-13-Methyl-1,2,3,6,7,8,9,10,11,12,13,14,16,17-Tetradecahydro-15H-Cyclopenta [a] Phenanthren-3-One And Esters Thereof
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5449795-A
优先权日:1994-02-14
标 题 :Process for synthesis of steroidal allylic tert. alcohols
发明人：HOGENKAMP DERK J
权利人:COCENSYS INC
摘要:A method for the preparation of a steroidal allylic tertiary alcohol is disclosed which involves the deprotonation of a sulfoxide with a strong base which is capable of deprotonating the methine proton which is α to the sulfoxide, in an inert solvent to give the anion; reaction of the anion with a steroidal spiro-2'-oxirane to give a steroidal γ-hydroxysulfoxide; and thermolysis in the presence of a base other than calcium carbonate to give the steroidal allylic tertiary alcohol.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: MARTINEZ MONTES EA, BAGNATI EP, ZAPATA AC, BUR GE. [Clinical trial of a new luteoid: norvinisterone]. Dia Med. 1960 Mar 3;32:194-7. Spanish.
合成参考文献
参考文献:10.1007/s11783-022-1558-z
摘要:Liang J, Luo Y, Li B, Liu S, Yang L, Gao P, Feng L, Liu Y, Du Z, Zhang L. Removal efficiencies of natural and synthetic progesterones in hospital wastewater treated by different disinfection processes. Frontiers of Environmental Science & Engineering. 2022 Mar 04;16(10):126. doi: 10.1007/s11783-022-1558-z.
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