📜4-溴-1-丁醇置于sodium Azide体系中,用 水,丙酮 作为反应溶剂,以60%的收率获得产物4-叠氮基丁烷-1-醇 参考文献:Synthesis And Self-Assembly Of Phthalocyanine-Tethered Block Copolymers 标题:Synthesis And Self-Assembly Of Phthalocyanine-Tethered Block Copolymers 摘要:通过原子转移自由基聚合和"点击"化学方法合成了带有酞菁的新型嵌段共聚物.这些嵌段共聚物和酞菁之间通过π-π相互作用进行微相分离,形成自组装的纳米结构. DOI:10.1039/c4Tc02778G
专利号:WO-2024182268-A1 优先权日:2023-02-27 标 题 :Liquid phase peptide support synthesis of peptides and peptidomimetics 发明人:HAN AMY 权利人:REGENERON PHARMA 摘要:The present invention provides compounds useful as support for liquid phase organic synthesis e.g., liquid phase organic synthesis of peptides and peptidomimetics. In one aspect, the present invention provides a compound having a structure of Formula (I) where R1, R2, R3, m, and n are as described herein and methods of making and using same.
专利号:US-11708320-B2 优先权日:2018-06-29 标 题:Environmentally-friendly hydroazidation of olefins 发明人:XU HAO 权利人:UNIV GEORGIA STATE RES FOUND 摘要:The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.
专利号:US-2024109924-A1 优先权日:2021-01-29 标 题 :Ip4-4,6 substituted derivative compounds 发明人:PÉREZ FERRER MARÃ?A DEL MAR; FERRER REYNÉS MIQUEL DAVID; BASSISSI MOHAMAD FIRAS; SALCEDO ROCA CAROLINA; SERRA COMAS CARME; CATENA RUIZ JUAN LORENZO; LLEBARIA SOLDEVILA AMADEU; ORTEGA CASTRO JOAQUÃ?N; PERELLÓ BESTARD JOAN 权利人:SANIFIT THERAPEUTICS S A 摘要:The present invention provides IP4-4,6 substituted derivatives, their methods of synthesis and their uses. In some aspects, the IP4-4,6 derivative is a compound of formula I wherein R1, R3, R7, and R11 are OPO32−, and R5 and R9 are selected from the group consisting of —O(Alkyl)nX, —O(Alkyl)yCy(Alkyl2)y-Z, —O(Alkyl)yA(Alkyl)y-Z′, and their thiophosphate analogs. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for the treatment of diseases and conditions such as pathological crystallization-related diseases and conditions.