CAS: 383-62-0; Ethyl 2-Chloro-2,2-Difluoroacetate

上下游产品

CAS号64-17-5 乙醇 | CAS号76-04-0 一氯二氟乙酸 | CAS号354-24-5 氯二氟乙酰氯 | CAS号1895-39-2 二氟氯乙酸钠 | CAS号648-48-6 1.1.2.2-Tetrafl... | CAS号1717-64-2 1,2-dichloro-1,... | CAS号381-73-7 二氟乙酸 | CAS号454-31-9 二氟乙酸乙酯 | CAS号76-04-0 一氯二氟乙酸 | CAS号1524-26-1 1,1,1-三氟丁烯-3 | CAS号436799-32-5 5-溴-2-(三氟甲基)吡啶 | CAS号384-67-8 一氯二氟苯乙酮 | CAS号2063-17-4 4-氯-4,4-二氟乙酰乙酸乙酯 | CAS号153587-11-2 3-二氟甲氧基-4-甲氧基苯甲醛 | CAS号1544-86-1 4-(二氟甲氧基)硝基苯 | CAS号141546-96-5 3-(二甲氨基)-3-乙氧基-...

氯(二氟)乙酰氯 以 乙醇 作为反应溶剂,化学反应生成 二氟氯乙酸乙酯
参考文献:Process For Producing Carboxylic Acid Esters From Carboxylic Acid
标题:Process For Producing Carboxylic Acid Esters From Carboxylic Acid
摘要:一种从羧酸卤化物或羧酸酐通过在"翁盐"或金属羧酸盐的催化作用下与醇反应来制备羧酸酯的方法,该方法可以在技术上简单的方式获得无水形式产物的高收率.这个过程特别适合于制备1,1,1-三氟乙基三氟醋酸酯.

专利信息

专利号:US-8853410-B2
优先权日:2009-04-30
标 题:Process for preparing substituted isoxazoline compounds and their precursors
发明人：RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN
权利人:RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN; BASF SE
摘要:The present invention relates to a new method of preparing halogenated styrene compounds of formula (VIII) n nwhich are precursors in the process of synthesis of substituted isoxazoline compounds of formula (I)n n nwherein R 1 to R 5 , R 8 and R 9 are described as in the description.n n The present invention relates further to the synthesis of compounds of formula (I) starting from acetophenones. The desired styrenes of formula are prepared from the appropriate substituted acetophenone. Asides bromo anilines react with formoxime. Obtained oximes undergo a cycloaddition with the styrenes and give isoxazolines. Compounds of formula (I) can then be prepared in a palladium catalyzed carbonylative amination reaction of the isoxazolines.

专利号:WO-2008081282-A2
优先权日:2006-12-20
标 题:Process for the synthesis of n9-(3,5-dichloro-4-pyridyl)-6- difluoromethoxybenzo(4,5)furo(3,2-c)pyridine-9-carboxamide and salts thereof

专利号:US-8445510-B2
优先权日:2010-05-14
标题 :Fused bicyclic kinase inhibitors
发明人：MULVIHILL MARK J; STEINIG ARNO G; CREW ANDREW PHILIP; JIN MEIZHONG; KLEINBERG ANDREW; LI AN-HU; WANG JING
权利人:MULVIHILL MARK J; STEINIG ARNO G; CREW ANDREW PHILIP; JIN MEIZHONG; KLEINBERG ANDREW; LI AN-HU; WANG JING; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula I, as shown below and defined herein: n n n n n n n n n n pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of RON, MET or ALK. This Abstract is not limiting of the invention.

专利号:WO-2011006000-A1
优先权日:2009-07-08
标题 :Berberine derivatives useful for modulating lipid levels and their methods of synthesis

专利号:CN-117003604-A
优先权日:2023-07-14
标题 :Synthesis method and process of allyl fluoroalkyl compound