CAS: 35694-04-3; 2,2',3,3',5,5'-Hexachlorobiphenyl

该化合物是一种氯化联苯化合物,其分子结构确定,其特点是2,2',3,3',5,5'和5'位置有6个氯替代物,这种配置具有很高的化学稳定性和抗降解性,使其在需要惰性材料的专门工业应用中有用.其特征清晰的结构允许精确的分析和研究应用,特别是在环境和毒理学研究中,作为多氯联苯(PCB)分析的参考标准.由于其持久性,处理需要严格遵守安全协议,以减轻环境和健康风险.该化合物的一贯纯性和稳定性使它成为涉及多氯联苯行为和补救的科学调查的可靠选择.

英文名称2,2',3,3',5,5'-Hexachlorobiphenyl
中文名称2,2',3,3',5,5'-六氯联苯
IUPAC名称1,2,5-trichloro-3-(2,3,5-trichlorophenyl)benzene
其它别名2,2',3,3',5,5'-Hexachlorobiphenyl; 2,3,5,2',3',5'-Hexachlorobiphenyl
CAS编号35694-04-3
MFCD编号:MFCD00152533
FDA UNII编号:P7EUD9W45V
分子式:C12H4Cl6分子量:360.88
产品CID: 1365484
产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃

相似结构搜索
InChIKey: AJKLKINFZLWHQE-UHFFFAOYSA-N
1S/C12H4Cl6/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)18/h1-4H
计算化学: 氢键受体数*氢键供体数*可旋转键数1.0

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
危险等级9
UN编号2315
包装等级II
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

2,3,5,2',3',5'-Hexachloro-biphenyl-4,4'-diamine 1,2,5-trichloro-3-iodobenzene 2,2',5,5'-tetrachloro-4,4'-diaminobiphenyl

合成工艺路线路线简述

📜2,2',5,5'-四氯二苯胺置于氯体系中,用二氯甲烷用作溶剂,化学反应生成2,2',3,3',5,5'-六氯联苯
参考文献:多氯联苯的质谱
标题:多氯联苯的质谱
摘要:几种二氯和四氯联苯的质谱表明,在裂解之前,氯在分子离子中的两个苯环上均是随机化的.2,2'-和2,6-二氯-,2,2',4,4'-,2,2',5,5'-,2,3,5,6-和2除外2',6,6'-四氯联苯都含有两个或多个与ph-Ph键邻位的氯原子,它们的亚稳离子强度由m-> M-Cl 2引起反应明显不同于其他异构体.大多数异构化合物的主离子光谱相似,分子离子连续损失cl..此过程通常伴随着从较低氯同系物(2)-(5)排出hcl,但只有将cl.排出的反应才伴随有亚稳离子.二氯和四氯异构体的离子动能谱证实了建议的裂解途径.
Doi:10.1039/p19720000686