CAS: 34612-80-1; Tetrasodium Dicarboxymethyl Aspartate

专利信息

专利号:US-11975061-B2
优先权日:2018-09-05
标题:Protective immunity enhanced Salmonella vaccine (PIESV) against Brucella spp
发明人：CURTISS III ROY
权利人:UNIV FLORIDA
摘要:Bacterial pathogens have evolved means to succeed as pathogens by infecting without recognition by receptors triggering innate immunity, by suppressing induction of immunity and by inducing immune responses to antigens that confer no protectives immunity. Embodiments described herein circumvent these abilities in Salmonella so as to provide a vector system that induces maximal protective immune responses. Another major problem in using live attenuated bacterial vaccine vectors is the accumulation of attenuating mutations that confer a virulence and safety but which decrease the ability of the vaccine to invade cells in the MALT to colonize and persist in internal effector lymphoid tissues. The embodiments disclosed herein solve this problem in multiple ways by using regulated delayed in vivo shut off of virulence genes, regulated delayed synthesis of recombinant protective antigens and regulated delayed lysis in vivo to confer biological containment with no persistence of vaccine cells and no survival if excreted.

专利号:US-3637511-A
优先权日:1969-05-19
标题:Detergent formulations
发明人：YANG MEILING T
权利人:ETHYL CORP
摘要:To obviate eutrophication of water, nonphosphorus detergent builders are provided. These are the water-soluble salts of N,N,di(carboxymethyl)-aspartic acid (e.g., the tetrasodium salt thereof). Conventional detergent actives may be used with these builders. Synthesis of the builders is described.

专利号:WO-2025016203-A1
优先权日:2023-07-18
标题 :Method for producing l-arginine using recombinant escherichia coli, and recombinant bacterium used therein
发明人：XIE XIXIAN; JIANG SHUAI; WU HEYUN; MA QIAN; LI RAN; MENG GANG; ZHAO CHUNGUANG; WEI AIYING; JIA HUIPING
权利人:NINGXIA EPPEN BIOTECH CO LTD
摘要:A method for producing L-arginine using a recombinant Escherichia coli, and a recombinant bacterium used therein. Specifically, the present invention relates to a method for producing L-arginine using a recombinant Escherichia coli, and a recombinant bacterium used therein. The recombinant Escherichia coli is a recombinant bacterium obtained by means of over-expressing a gene encoding a cyanate transporter in a receptor Escherichia coli, or a recombinant bacterium obtained by means of over-expressing a gene encoding a carbonic anhydrase in a receptor Escherichia coli. The cyanate transporter is a protein having an amino acid sequence of SEQ ID NO: 4, and the carbonic anhydrase is a protein having an amino acid sequence of SEQ ID NO: 5. By means of regulating the expression of the cyanate transporter or carbonic anhydrase, the yield of arginine is significantly improved. The method provides a new line of thought for the synthesis of bio-based L-arginine, and has wide application space and market prospects.