CAS: 3420-59-5; 1-(3-Hydroxyfuran-2-yl)Ethanone

该化合物是一种来自呋喃的氯酮化合物,其特征是位于呋喃环的三处的氢氧基酮组.这一结构特征在有机合成中具有回活动性和潜在效用,特别是作为制药,农用化学品或特殊化学品的中间体.氢氧和碳基功能的存在都允许多种化学改变,包括凝结,氧化或核循环添加反应.其呋喃核心可能有助于在环流化学中的应用或作为生物活性分子的前体.该化合物的纯性和稳定性对于可复制合成结果至关重要,因此适合需要精确分子护具的研究和工业应用.

结构式图片

MSDS等安全信息

    合成工艺路线路线简述

      📜1-[3-(α-D-Glucopyranosyloxy)-2-Furanyl]-1-Ethanone 反应生成1-(3-羟基-2-呋喃基)乙酮
      参考文献:Isolation Of 3-O-α-D-Gluco-And 3-O-β-D-Galacto-Pyranosyloxy-2-Furyl Methyl Ketones From Nonenzymic Browning Of Maltose And Lactose With Secondary Amino Acids
      标题:Isolation Of 3-O-α-D-Gluco-And 3-O-β-D-Galacto-Pyranosyloxy-2-Furyl Methyl Ketones From Nonenzymic Browning Of Maltose And Lactose With Secondary Amino Acids
      摘要:
      Doi:10.1016/0008-6215(83)88160-9

      海关参考信息

      专利信息


      专利号:US-2006030625-A1
      优先权日:2004-08-06
      标 题 :Dietary neurotransmitter precursors for balanced synthesis of neurotransmitters
      发明人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
      权利人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
      摘要:Dietary supplements for treating a neurotransmitter deficiency include one or more precursors of the deficient neurotransmitter and a cofactor for activating in vivo enzymatic synthesis of the deficient neurotransmitter. The dietary supplements can also include an appropriate neurotransmitter, such as an amino acid. When administered through the oral mucosa, increases in levels of the deficient neurotransmitters and relief from deficiency symptoms are obtained.

      专利号:US-2017204442-A1
      优先权日:2014-05-29
      标题 :Enzymatic synthesis of soluble glucan fiber
      发明人:DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG
      权利人:DU PONT
      摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

      专利号:US-11692058-B2
      优先权日:2021-02-26
      标题:Synthesis of functional polyurethanes and polyesters from biomass-derived monomers
      发明人:CHANG HOCHAN; HUBER GEORGE W; DUMESIC JAMES A
      权利人:WISCONSIN ALUMNI RES FOUND
      摘要:A method of making polyesters and polyurethanes from biomass-derived polyols. The polyol is biomass-derived and has the structure:wherein dashed bonds are single or double bonds and R is selected from the group consisting of —OH and â• O. Polyurethanes are made by reacting the polyol with a diisocyanate. Polyesters are made by reacting the polyol with a dicarboxylic acid.

      专利号:US-9090550-B2
      优先权日:2010-07-30
      标 题:Microwave assisted synthesis of dehydrated sugar derivatives hydroxymethylfurfural, levulinic acid, anhydrosugar alcohols, and ethers thereof
      发明人:HOWARD STEPHEN J; SANBORN ALEXANDRA J
      权利人:HOWARD STEPHEN J; SANBORN ALEXANDRA J; ARCHER DANIELS MIDLAND CO
      摘要:Methods for the production of dehydrated sugars and derivatives of dehydrated sugars using microwave (MW) irradiation and methods of purifying the same are described. The dehydrated sugars derivatives include 5-hydroxymethyl-2-furfural (HMF) and anhydrosugar alcohols such as sorbitans and isosorbide. The derivatives include HMF ethers, levulinic acid esters, and ether derivatives of the anhydrosugar alcohols. The described methods require lower reaction temperatures and shorter reaction times than similar non microwave mediated reactions known in the art. Typical reaction conditions are 120-210° C., and typical reaction times are 30 minutes or less.

      专利号:US-2023295102-A1
      优先权日:2020-08-11
      标 题 :A process for preparation of 2, 5-furan dicarboxylic acid from 5-hydroxymethyl furfural
      发明人:DHEPE PARESH LAXMIKANT; SONONE KALYANI GAJANANRAO; LOKHANDE PRIYA LAXMANRAO
      权利人:COUNCIL SCIENT IND RES
      摘要:The present invention provides a process for the synthesis of furan dicarboxylic acid (FDCA) from glucose or crude hydroxy methyl furfural (HMF) using mixed metal oxides catalyst. The present invention further provides a process for preparation of the mixed metal oxides catalyst.

      专利号:US-2017198323-A1
      优先权日:2014-05-29
      标题:Enzymatic synthesis of soluble glucan fiber
      发明人:CHENG QIONG; DICOSIMO ROBERT; OUWEHAND ARTHUR; YOU ZHENG; PAYNE MARK S; PRASAD JAHNAVI CHANDRA
      权利人:DU PONT
      摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

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      主要参考文献


      1: Heine KB, Clegg JK, Heine A, Gloe K, Gloe K, Henle T, Bernhard G, Cai ZL, Reimers JR, Lindoy LF, Lach J, Kersting B. Complexation, computational, magnetic, and structural studies of the Maillard reaction product isomaltol including investigation of an uncommon π interaction with copper(II). Inorg Chem. 2011 Feb 21;50(4):1498-505. doi: 10.1021/ic102117d. Epub 2011 Jan 26. Epub 2006 Jan 20. doi: 10.1016/j.foodchem.2015.03.097. Epub 2015 Mar 28. German. German. German.

      合成参考文献


      参考文献:10.1021/ic025612u
      摘要:Cecconi F, Ghilardi CA, Ienco A, Mariani P, Mealli C, Midollini S, Orlandini A, Vacca A. Different complexation properties of some hydroxy keto heterocycles toward beryllium(II) in aqueous solutions: experimental and theoretical studies. Inorg Chem. 2002 Jul 29;41(15):4006–17. doi: 10.1021/ic025612u.
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