CAS: 2883-98-9; (E)-1,2,4-Trimethoxy-5-(Prop-1-En-1-yl)Benzene

上下游产品

顺式-2,4,5-三甲氧基-1-丙烯基苯 Beta-Asarone 5273-86-9
1,2,4-三甲氧基-5-丙烯基苯 Asarone 494-40-6
2-丙烯醛,3-(2,4,5-三甲氧苯基)- 2,4,5-Trimethoxy Cinnamaldehyde 106128-88-5
2-丙烯醛,3-(2,4,5-三甲氧苯基)- Trans 2,4,5-Trimethoxy Cinnamaldehyde 99217-07-9
2-Methoxy-5-Trans-Propenyl-Hydroquinone
2-甲氧基-5-(1-丙烯-1-基)苯酚 Isochavibetol 19784-98-6
2,4,5-三甲氧基苯甲醛 Asaraldehyde 4460-86-0
1,2,4-三甲氧基-5-丙基-苯 1-Propyl-2,4,5-Trimethoxybenzene 6906-65-6 1-Allyl-2,4,5-Trimethoxybenzene 5353-15-1 (E)-1-Bromo-4,5-Dimethoxy-2-(Prop-1-En-1-yl)Benzene 65720-03-8

顺式-2,4,5-三甲氧基-1-丙烯基苯置于cobalt(II) Chloride,2,2'-Bis(Diphenylphosphino)Phenylamine,三乙基硼氢化钠体系中,用 甲苯 用作溶剂,化学反应 1.08H,以99%的收率获得细辛脑
参考文献:钴催化烯烃的z到e异构化:(e)-β取代的苯乙烯的一种方法.
标题:钴催化烯烃的z到e异构化:(e)-β取代的苯乙烯的一种方法.
摘要:开发了使用酰胺基-二膦配体的高效钴催化的β-取代的苯乙烯的z到e异构化方法,提供了具有非常好功能耐受性和高立体选择性的(e)异构体.使用(z)-和(e)-烯烃的混合物作为起始原料,该反应可以在催化剂负载为0.1Mol%的情况下按比例放大至克级.初期机理研究表明,在实验和dft计算的支持下,钴(i)氢化物和苄基钴可能参与了反应.
Doi:10.1021/acs.Orglett.0C00072

专利信息

专利号:US-7872160-B2
优先权日:2008-03-31
标题:Single pot process for the regioselective synthesis of neolignan framework asarones
发明人：UPPULURI VENKATA MALLAVADHANI; AKELLA VENKATA SUBRAHMANYA SUDHAKAR; MAHAPATRA ANITA
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a single pot process for the regioselective synthesis of neolignan framework [3(R)-Ethyl-2(S)-methyl-3-(2″,4″,5″-trimethoxyphenyl)-1-(2′,4′,5′-trimethoxyphenyl)propane from toxic β-isomer rich asarone using montmorillonite acidic clay by employing microwave organic reaction enhancement (MORE) chemistry. This may be useful as versatile synthetic protocol for the synthesis of a large number of lignan and neolignan frameworks.

专利号:US-2010099856-A1
优先权日:2008-03-31
标题 :Single pot process for the regioselective synthesis of neolignan framework asarones

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优先权日:2015-09-07
标题:A kind of green solvent for the synthesis of α-asarone and its application method

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优先权日:2001-03-22
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优先权日:2018-08-08
标题 :A kind of α-asarone synthesis process

专利号:CN-120025234-A
优先权日:2025-02-05
标 题:A kind of synthesis method of α-asarone