CAS: 14191-95-8; 2-(4-Hydroxyphenyl)Acetonitrile

相似化合物

156-38-7 17194-82-0 25263-44-9

上下游产品

p-aminophenylacetonitrile [2-hydroxyimino-3-(4-hydroxyphenyl)]propionic acid acetic anhydride 2L-Tyr-NH2 4-ethoxyphenylacetic acid 4'-ethoxyphenylacetamide 2,4'-dihydroxy-4,6-dimethoxy-deoxybenzoin 2,4,4',6-tetrahydroxydeoxybenzoin

L-酪氨酸置于氢氧化钾,碘苯二乙酸体系中,用 甲醇 用作溶剂,化学反应 1.5H,以52%的收率获得对羟基苯乙腈
参考文献:使用高价碘裂解nh 2末端酪氨酰-肽键
标题:使用高价碘裂解nh 2末端酪氨酰-肽键
摘要:用c 6 H 5 I(oac)2-Meoh-Koh裂解nh 2-酪氨酸二肽可产生4-(甲氧基甲基)苯酚.
Doi:10.1039/c39850000974

专利信息

专利号:US-2009062555-A1
优先权日:2007-08-28
标 题 :Synthesis of Isoflavone
发明人：HARMS ARTHUR E
权利人:HARMS ARTHUR E
摘要:The invention provides a process of manufacturing an isoflavone of the general formula 7 n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 each independently are H, OH, or an alkoxy, provided at least one of R 1 , R 2 , R 3 , and R 4 being OH, and one being alkoxy, or at least 2 groups being OH, comprising providing ketone (3) n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 are as stated above, combining (3) with trialkylortho formate, and a Lewis or Bronsted acid to produce the isoflavone, precipitating the isoflavone.

专利号:US-7339065-B2
优先权日:2003-07-21
标题 :Design and synthesis of optimized ligands for PPAR
发明人：AVERY MITCHELL A; PERSHADSINGH HARRIHAR A
权利人:BETHESDA PHARMACEUTICALS INC; UNIV MISSISSIPPI
摘要:This invention provides new chemical entities useful for treating a variety of clinical disorders including those that are influenced by the activity of peroxisome proliferator activated receptors (PPAR). The structures of the compounds and methods to design, make and use the compounds are provided. Compounds and methods for administering therapeutic compositions comprising the compounds in cases of the disease psoriasis are provided. An exemplary compound having the formula compound is 5adamantan-2-yl-pentanoic acid {2-[4-(2,4-dioxo-thiazolidin-5-yl-methyl)-phenoxy]-ethyl}-methyl-amide is provided.

专利号:US-2006165683-A1
优先权日:2001-12-05
标题:Methods and compositions for control of bone formation via modulation of sympathetic tone
发明人：KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
权利人:KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
摘要:This invention relates to methods for treatment, diagnosis and prevention of bone disease and comprises methods including measurement and modulation of sympathetic tone and leptin activity. Alteration of sympathetic tone in bone disease can be accomplished by decreasing or increasing leptin synthesis, leptin receptor synthesis, leptin binding to the leptin receptor, and leptin receptor activity. Alteration of sympathetic tone in bone disease can also be accomplished in the foregoing manner, in combination with traditional sympathetic nervous system agonists and/or antagonists, such as, but not limited to, a dopamine β hydroxylase antagonist or a β adrenergic antagonist for treatment or prevention of osteoporosis.

专利号:US-2009062572-A1
优先权日:2006-07-26
标 题 :Processes for the synthesis of O-desmethylvenlafaxine

专利号:US-2007099969-A1
优先权日:2003-07-21
标题 :Design and synthesis of optimized ligands for ppar

专利号:SI-21559-A
优先权日:2003-08-29
标题 :Method for the synthesis of amidines and their derivatives on solid carriers and its use for the production of combinatorial libraries