CAS: 613-73-0; 1,2-Phenylenediacetonitrile

该化合物是有机化合物,结构特征为:一个苯环,配有与相邻碳原子相连的两组碳原子,该化合物一般是室内温度下一种白色至浅黄色晶体固体,在乙醇和丙酮等有机溶剂中可溶解,但在水中溶解性有限;该细胞组的存在使分子极化,影响其再活动性以及与其他物质的相互作用. 1,2-苯乙酰丙烯三烯经常用于有机合成,并可作为各种化学反应的前体,包括形成其他功能组.此外,该化合物可能展示生物活动,使其在制药研究中引起兴趣.在处理该化合物时,应注意安全防范措施,因为如果摄入或吸入,可能会对健康造成危害.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号773837-37-9 sodium cyanide | CAS号91-13-4 α,α'-二溴邻二甲苯 | CAS号95-47-6 邻二甲苯 | CAS号151-50-8 氰化钾 | CAS号140-29-4 苯乙腈 | CAS号75-05-8 乙腈 | CAS号13435-20-6 氰化四乙基铵 | CAS号89-92-9 2-甲基苄基溴 | CAS号4424-20-8 2,3,4,5 -四氢-1H ... | CAS号42988-81-8 2,2'-o-phenylen... | CAS号3029-30-9 萘-1,4-二腈 | CAS号75-64-9 叔丁胺 | CAS号87-62-7 2,6-二甲基苯胺 | CAS号75-31-0 异丙胺 | CAS号95-53-4 邻甲苯胺 | CAS号108-91-8 环己胺 | CAS号95-68-1 2,4-二甲基苯胺 | CAS号88-05-1 2,4,6-三甲基苯胺

合成工艺路线路线简述

  • 合成目标产物 1,2-Bis(Cyanomethyl)Benzene 主要起始原料 O-Xylene
  • (文献来源)合成步骤主要原料 O-Xylene
📜邻二甲苯置于溴体系中,用 乙醇,水 作为反应溶剂,化学反应 2.0H,反应生成 1,2-苯二乙腈
参考文献: Phenylene Oxo-Diester Plasticizers And Methods Of Making[fr] Plastifiants Oxo-Diesters De Phénylène Et Procédés De Fabrication
标题: Phenylene Oxo-Diester Plasticizers And Methods Of Making[fr] Plastifiants Oxo-Diesters De Phénylène Et Procédés De Fabrication
摘要:一种制造非邻苯二甲酸酯,1,2-苯基氧代二酯增塑剂用于聚合物组合物的方法,通过选择性加氢萘形成部分加氢萘,将部分加氢萘氧化成苯基二酸,然后酯化苯基二酸与氧代醇形成1,2-苯基氧代二酯.另外一种制造苯基氧代二酯增塑剂的方法是通过选择性溴化二甲苯形成双溴甲基苯,催化羧酸酯化溴化合物形成苯基二乙酸酯,然后通过酯交换反应形成苯基氧代二酯.

海关参考信息

专利信息


专利号:US-4918222-A
优先权日:1984-07-27
标 题 :Process for synthesis of N-acetylglycine
发明人:LIN JIANG-JEN; KNIFTON JOHN F; YEAKEY ERNEST L
权利人:TEXACO INC
摘要:An N-acetylglycine is manufactured by reacting paraformaldehyde with an acetamide and carbon monoxide in the present of a cobalt-containing catalyst promoted by a sulfoxide or dinitride compounds. The presence of sulfoxide or dinitrile ligands are essential for the high yield synthesis of N-acetylglycine and good cobalt recovery.

专利号:US-5629394-A
优先权日:1992-12-17
标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
发明人:CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
权利人:EXXON CHEMICAL PATENTS INC
摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

专利号:US-4201868-A
优先权日:1975-03-05
标 题:Reaction of methanol with synthesis gas
发明人:SLINKARD WILLIAM E
权利人:CELANESE CORP
摘要:A process for the reacting of methanol with carbon monoxide and hydrogen to produce increased amounts of methyl acetate, acetaldehyde and dimethyl acetal utilizing a catalyst comprising a cobalt carbonyl in complex with an organic nitrogen ligand.

专利号:US-5336745-A
优先权日:1988-06-28
标题 :Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators
发明人:CHERADAME HERVE M; LUNDBERG ROBERT D; CHEN FRANK J; HABIMANA JEAN DE LA CROIS
权利人:EXXON CHEMICAL PATENTS INC
摘要:A method is provided for the direct synthesis of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or of tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

专利号:JP-H0284403-A
优先权日:1988-06-28
标题 :Direct synthesis of nitrogen-containing polymers by cationic polymerization

专利号:DE-68928057-T2
优先权日:1988-06-28
标题 :Direct synthesis of nitrogen-containing polymers by cationic polymerization

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Palladium(II)-Catalyzed Desulfitative Synthesis Of Aryl Ketones From Sodium Arylsulfinates And Nitriles: Scope, Limitations, And Mechanistic Studies
作者:Bobo Skillinghaug,Christian Sköld,Jonas Rydfjord,Fredrik Svensson,Malte Behrends,Jonas Sävmarker,Per J. R. Sjöberg,Mats Larhed |发布日期:2014.12.19
摘要:The Desulfitative Synthesis Of Aryl Ketones From Nitriles Was Also Compared To The Corresponding Transformation Starting From Benzoic Acids. Comparison Of The Energy Profiles Indicates That The Free Energy Requirement For Decarboxylation Of 2,6-Dimethoxybenzoic Acid And Especially Benzoic Acid Is Higher Than The Corresponding Desulfitative Process For Generating The Key Aryl Palladium Intermediate. The

合成参考文献


摘要:Meigh, J.-P. K., Science of Synthesis, (2004) 17, 858.
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