专利号:US-2025271423-A1 优先权日:2022-04-22 标 题 :Polymer conjugate for blocking of non-specific interactions in immunochemical assays, method of its synthesis and use thereof 发明人:ETRYCH TOMAS; SUBR VLADIMIR; KOSTKA LIBOR; MOOS JIRI; PLICKA JAN 权利人:USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I; I&I PRAGUE S R O; ELISA DEV S R O 摘要:The present invention relates to macromolecular blockers of non-specific interactions of an analyte and other components of the analytical system with the solid phase, which considerably decreases the non-specific interactions during the assay. The macromolecular blocker comprises synthetic copolymer or homopolymer, selected from the group comprising polyacrylamide, polymethacrylamide, polyacrylate, polymethacrylate, poly(N-(2-hydroxypropyl)methacrylamide), poly(2-oxazoline); to which at least one hydrophobically-active anchor is attached via a covalent bond, said hydrophobically-active anchor enabling suppression of non-specific interactions in immuno assays. The invention further relates to a method of preparing and to the use of said macromolecular blockers for capturing of specific antibodies or antigens or other molecules on the surface of the solid phase. The present invention enables to replace animal-derived proteins with a synthetic macromolecular blocker that is not only more effective in blocking activity itself, but it is also defined in its structure, has high batch-to-batch reproducibility, and does not need to be tested for the presence of viruses and other pathogens.
专利号:US-2024130359-A1 优先权日:2022-09-28 标题 :Antimicrobial coating compositions 发明人:HERCHEN STEPHEN ROBERT; LIANG RONG-CHANG; JANSSEN CHRISTIAN EWALD 权利人:POLAROID IP B V 摘要:Described herein are quaternary ammonium polymers and interpenetrating polymer networks and compositions thereof with broad spectrum antimicrobial properties that produce fast acting, long lasting, non-toxic and non-allergenic colorless and transparent durable surface coatings that are resistant to water and common solvents. The surface coatings are easy and cost effective to produce from readily-available materials using versatile synthesis enabling a wide range of chemical variations. They are readily applied to a wide range of surfaces and materials, and no materials leach out of the coatings.
专利号:CN-104829600-B 优先权日:2015-05-05 标 题 :A kind of synthesis technique of the intermediate in synthesizing rosuvastatin spit of fland
专利号:CN-108250222-A 优先权日:2018-01-30 标题:Synthesis and application of (D-A)n+1D oligomer photovoltaic donor materials based on benzodithiophene-4,8-dione
专利号:CN-104829600-A 优先权日:2015-05-05 标 题:A kind of synthesis technique of the intermediate of synthetic rosuvastatin
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