CAS: 546-57-6; Erythralosamine

上下游产品

erythromycin C erythromycin

📜红霉素置于盐酸体系中,化学反应生成 红霉糖胺
参考文献:Erythromycin. I. Properties And Degradation Studies1
标题:Erythromycin. I. Properties And Degradation Studies1
摘要:
DOI:10.1021/ja01641A005

专利信息

专利号:US-2006074032-A1
优先权日:2000-11-29
标题 :Synthesis and separation of optically active isomers of erythromycin and their biological actions
发明人：SOMBERG JOHN; RANADE VASANT
权利人:ACADEMIC PHARM INC
摘要:The present invention provides methods for purifying and using optically active isomers of erythromycin as well as compositions comprising such optically active isomers. Such optically active isomers having desired actions as an antibiotic substantially separable from undesirable effects on GI motility and the cardiac potassium channels such that the cardiac action potential is not prolonged and the QT interval on the surface EKG (electrocardiogram) is not increased, such that the erythromycin can be useful for more effective therapy of systemic infections. Also disclosed are methods for assaying the levels of such isomers present in the biological fluids.

专利号:WO-02064608-A1
优先权日:2000-11-29
标 题:Synthesis and separation of optically active isomers of erythromycin and their biological actions
发明人：SOMBERG JOHN C; RANADE VASANT
权利人:ACADEMIC PHARM INC; SOMBERG JOHN C; RANADE VASANT
摘要:The present invention provides methods for purifying and using optically active isomers of erythromycin as well as compositions comprising such optically active isomers. Such optically active isomers having desired actions as an antibiotic substantially separable from undesirable effects on GI motility and the cardiac potassium channels such that the cardiac action potential is not prolonged and the QT interval on the surface EKG (electrocardiogram) is not increased, such that the erythromycin can be useful for more effective therapy of systemic infections. Also disclosed are methods for assaying the levels of such isomers present in the biological fluids.

专利号:EP-1339731-A1
优先权日:2000-11-29
标题:Synthesis and separation of optically active isomers of erythromycin and their biological actions

专利号:US-2004067898-A1
优先权日:2001-11-27
标 题 :Synthesis and separation of optically active isomers of erythromycin and their biological actions