CAS: 39959-54-1; (3-Bromophenyl)Methanamine Hydrochloride

上下游产品

CAS号932-77-4 3-溴苄氯 | CAS号337535-82-7 N-(3-溴苯基)乙酰胺 | CAS号171663-13-1 1-(B°C-氨甲基)-3-溴苯 | CAS号170853-04-0 叔丁基N-(3-甲酸基苄基)氨基甲酸酯

📜间溴苯甲腈置于[2,6-η6:η1-Bis(2,4,6-Trimethylphenyl)Phenylthiolato]Triethylphosphineruthenium(II)Tetrakis[3,5-Bis(Trifluoromethyl)Phenyl]Borate,Diethylphenylsilane,盐酸体系中,用 乙醚 用作溶剂,化学反应 19.0H,以99%的收率获得3-溴苄胺盐酸盐
参考文献:通过涉及协同 Si-H 键活化的催化氢化硅烷化完全化学选择性还原腈
标题:通过涉及协同 Si-H 键活化的催化氢化硅烷化完全化学选择性还原腈
摘要:报道了一种将腈催化氢化硅烷化至亚胺或胺氧化水平的化学选择性方法.化学选择性由所用的氢硅烷控制.腈到胺还原的有用性已被证明适用于各种芳香族和脂肪族腈,并且胺在水解后很容易以其盐酸盐的形式分离.这种彻底的腈还原在室温下进行.
Doi:10.1055/s-0036-1588441

专利信息

专利号:US-9102698-B2
优先权日:2007-03-14
标 题:Process for the synthesis of IB-MECA
发明人：BRUZINSKI PAUL; LIU XUEJUN; GIBB CAMERON; HERNANDEZ-ABAD PEDRO E
权利人:BRUZINSKI PAUL; LIU XUEJUN; GIBB CAMERON; HERNANDEZ-ABAD PEDRO E; CAN FITE BIOPHARMA LTD
摘要:The present disclosure provides a method for the synthesis of IB-MECA. More specifically, the present disclosure provides a simple and high yield method for Good Manufacturing Production (GMP) of IB-MECA. The method involves the reaction of 6-halopurine-9-riboside with a diol protecting reagent; oxidation of the primary alcohol in the diol protected 6-halopurine-9-riboside with a diol protecting reagent; oxidation of the primary alcohol in the diol protected 6-halopurine; reaction of the diol protected 6-halopurine with a nucleophile (e.g. methylamine); substitution of the halogen group with iodobenzylamine and removal of the diol protecting group.

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-2010087636-A1
优先权日:2007-03-14
标题:Process for the synthesis of ib-meca

专利号:WO-2008111082-A1
优先权日:2007-03-14
标题 :Process for the synthesis of ib-meca

专利号:DK-2137202-T3
优先权日:2007-03-14
标题:PROCEDURE FOR SYNTHESIS OF IB-MECA

专利号:HU-E034474-T2
优先权日:2007-03-14
标题:Method for the synthesis of IB-meca