CAS: 3198-30-9; P-Benzenedicarboxylate Dianion

📜4-甲基苯甲酸根置于ammonium Iron(II) Sulfate Hexahydrate,Nicotinamide Adenine Dinucleotide,还原型辅酶ⅰ体系中,用 Aq. Buffer 用作溶剂,化学反应 3.0H,反应生成对苯二甲酸酯(2-)
参考文献:Nadh 回收酶 Tsac 和 Tsad 为 Rieske 加氧酶化学再生还原当量
标题:Nadh 回收酶 Tsac 和 Tsad 为 Rieske 加氧酶化学再生还原当量
摘要:许多微生物使用生物和非生物分子作为碳和能量来源.这种足智多谋意味着一些微生物具有吸收环境中污染物的机制.其中一种生物体是睾酮丛毛单胞菌,它通过 Tsambcd 途径代谢 4-甲基苯磺酸盐和 4-甲基苯甲酸盐. Tsam 是一种 Rieske 加氧酶,它与还原酶 Tsab 一起消耗摩尔当量的 Nadh.在此步骤之后,注释的短链脱氢酶/还原酶和乙醛脱氢酶 Tsac 和 Tsad 各自重新生成摩尔当量的 Nadh.这种共存改善了对还原当量的化学计量添加的需要,因此代表了将里斯克加氧酶化学整合到生物催化应用中的有吸引力的策略.因此,在这项工作中,为了克服与 Rieske 非血红素铁加氧酶(rieske 加氧酶)协同作用的 Nadh 回收酶信息的缺乏,我们将 Tsac 的 X 射线晶体结构解析到了 2.18 å 的分辨率.利用这种结构,一系列底物类似物和蛋白质变体组合反应以及差示扫描荧光测定实验,我们确定了参与结合
Doi:10.1016/j.Jbc.2023.105222

专利信息

专利号:US-9000209-B2
优先权日:2011-07-22
标题:Method of regioselective synthesis of substituted benzoates
发明人：KRAUS GEORGE A
权利人:KRAUS GEORGE A; UNIV IOWA STATE RES FOUND INC
摘要:A method of synthesis of para-substituted benzoate esters and acids is provided, wherein the para-substituted regioisomer is obtained substantially free of the meta-substituted impurity, the method comprising contacting a coumalate ester or acid and an unactivated alkene at elevated temperature in the presence of a metal oxidation catalyst and an oxidant. The metal oxidation catalyst can be palladium, such as palladium on carbon, and the oxidant can be the oxygen gas in ambient air. The reaction can be carried out without solvent or in high boiling hydrocarbon solvents such as mesitylene. When the unactivated alkene is a monosubstituted alkene, yields of at least about 50 or 60% of para-substituted ester and acid products, respectively, are obtained, substantially free of the regioisomeric meta-substituted impurity.

专利号:US-3676484-A
优先权日:1970-02-10
标题 :Synthesis of hydroxyalkyl esters of carboxylic acids
发明人：SCRUGGS JACK G; BRADY DONNIE G
权利人:PHILLIPS PETROLEUM CO
摘要:Preparation of esters by reaction of halocarbinols with alkali metal carboxylates using phosphonium salts as catalysts to avoid otherwise undesired side reactions, such as polymerization, while providing effective yields of the desired esters.

专利号:US-8258298-B2
优先权日:2008-12-10
标 题 :Synthesis of morphine-6-glucuronide or one of the derivatives thereof
发明人：DLUBALA ALAIN; TRECANT CLAIRE; RIPOCHE ISABELLE
权利人:DLUBALA ALAIN; TRECANT CLAIRE; RIPOCHE ISABELLE; SANOFI SA
摘要:The disclosure relates to a method for preparing morphine-6-glucuronide or one of the deritives thereof comprising reacting a compound of formula (I): n nwherein R 1 is as defined in the disclosure,n nwith a glucuronic acid derivative of formula (II):n n nwherein PG, X, and R 4 are as defined in the disclosure,n nin the presence of an aromatic solvent and trimethylsilyl trifluoromethanesulfonate;n n(ii) reacting the product obtained in step (i) with a strong basic agent; and then (iii) recovering the product obtained in step (ii).

专利号:US-11891406-B2
优先权日:2019-03-14
标题:Conductivity enhancement of MOFs via development of MOFpolymer composite material
发明人：PEEDIKAKKAL ABDUL MALIK P; AL-BETAR ABDUL-RAHMAN; AL-MOUSA AMMAR HUSSAIN
权利人:UNIV KING FAHD PET & MINERALS
摘要:A method for enhancing the conductivity of MOF-5 by the development of an MOF-5 polymer composite material. The composite material incorporates a conductive polymer, preferably polyaniline, in the solvo-thermal synthesis pathway of MOF-5. The electrically conductive MOF-5 composite exhibits electric conductivity three orders of magnitude higher than that of MOF-5 while maintaining the crystallinity, robustness, and thermal stability of MOF-5.

专利号:US-7582653-B2
优先权日:2003-03-31
标 题 :Mercaptophenyl naphthyl methane compounds and synthesis thereof
权利人:COUNCIL SCIENT IND RES
摘要:Novel mercaptophenyl naphthyl methane compounds, their pharmaceutically acceptable salts and compositions comprised thereof are useful for the prevention or treatment of various medical indications associated with estrogen dependent diseases or syndromes related to osteoporosis, bone loss, bone formation, cardiovascular disorders, neurodegenerative disorders, menopausal disorders, physiological disorders, diabetes disorders, prostatic carcinoma, cancer of breast, cancer of uterus, cancer of the cervix and cancer of the colon, threatened or habitual abortion, obesity, ovarian development or function, post-partum lactation and depression.

专利号:KR-20230153343-A
优先权日:2019-04-08
标 题:Synthesis of high-value products from polyethylene terephthalate