专利号:US-5879690-A 优先权日:1995-09-07 标题:Topical administration of catecholamines and related compounds to subcutaneous muscle tissue using percutaneous penetration enhancers 发明人:PERRICONE NICHOLAS V 摘要:Compositions for the topical treatment of sagging subcutaneous muscle and overlying cutaneous tissue contain an active ingredient exhibiting or producing catecholamine activity such as catecholamines and/or related compounds in a dermatologically acceptable carrier that contains at least one percutaneous penetration enhancer. Examplary catecholamines include adrenaline, norepinepherine, dopamine and their precursors; catecholamine precursors such as tyrosine and phenylalanine are preferred. Many embodiments, particularly those employing tyrosine and/or phenylalanine as a catecholamine precursor, further contain a neurotransmitter synthesis enhancer such as dimethylaminoethanol, and other co-factors such as vitamin B 6 and pantothenic acid or calcium pantothenate are included in the composition to enhance the action of the active ingredients. Other compounds that scavenge free radicals and antioxidants may also be added.
专利号:WO-0031028-A2 优先权日:1998-11-20 标 题 :Improved synthesis of bleach activators
专利号:US-6583095-B1 优先权日:1998-11-20 标题 :Synthesis of bleach activators 发明人:DUPONT JEFFREY SCOTT; DYKSTRA ROBERT RICHARD 权利人:PROCTER & GAMBLE 摘要:The present invention relates to an improved process for synthesizing organic compounds for use as bleach activators.
专利号:JP-2002530370-A 优先权日:1998-11-20 标题:Synthesis of improved bleach activator
专利号:CA-2349003-A1 优先权日:1998-11-20 标题 :Improved synthesis of bleach activators
专利号:CN-1333748-A 优先权日:1998-11-20 标 题:Improved Synthesis of Bleach Activators
1: Sommer E, Neubert RHH, Mentel M, Tuchscherer B, Mrestani Y, Wohlrab J. Dermal peptide delivery using enhancer molecules and colloidal carrier systems. Part III: Tetrapeptide GEKG. Eur J Pharm Sci. 2018 Nov 1;124:137-144. doi: 10.1016/j.ejps.2018.08.034. Epub 2018 Aug 27. Russian. Epub 2006 Jul 15.