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专利信息
专利号:US-8372971-B2
优先权日:2004-08-25
标 题:Heterocyclic compounds and methods of use
发明人:WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.
专利号:US-9181188-B2
优先权日:2002-02-11
标 题:Aryl ureas as kinase inhibitors
发明人:DUMAS JACQUES; SCOTT WILLIAM J; CHIEN DU-SCHIENG; NASSAR ALA; LEE WENDY; BJORGE SUSAN; MUSZA LASZLO L; RIEDL BERND
权利人:DUMAS JACQUES; SCOTT WILLIAM J; CHIEN DU-SCHIENG; NASSAR ALA; LEE WENDY; BJORGE SUSAN; MUSZA LASZLO L; RIEDL BERND; BAYER HEALTHCARE LLC
摘要:This invention relates to new aryl ureas and methods for their synthesis. The inventive compounds are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.