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CAS号67-56-1 甲醇 | CAS号5345-47-1 2-氨基烟酸 | CAS号74-88-4 碘甲烷 | CAS号1462-86-8 3-氨基吡啶-2-羧酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号37091-73-9 2-氯-1,3-二甲基氯化咪唑啉 | CAS号186581-53-3 重氮甲烷 | CAS号111477-17-9 咪唑并[1,2-a]吡啶-8-基甲醇 | CAS号213666-98-9 2-Pyridinamine,... | CAS号28907-30-4 Benzo[b][1,8]na... | CAS号877593-11-8 3-羟甲基嘧啶-2-氨基甲酸叔丁酯 | CAS号133427-07-3 咪唑并[1,2-A]吡啶-8-甲酸甲酯 | CAS号13438-65-8 2-氨基吡啶-3-甲酰胺 | CAS号1186189-28-5 4-羟基-2-氧代-1,2-二... | CAS号1418315-87-3 2-[(甲基磺酰基)氨基]-3... | CAS号136117-74-3 咪唑并[1,2-a]吡啶-8-甲醛 | CAS号167883-99-0 8-(氯甲基)咪唑并[1,2-...在 十二羰基三钌,5,5-二甲基-2-苯基-1,3,2-二氧硼杂,异丙醇体系中,化学反应 24.0H,以70%的收率获得2-氨基吡啶-3-甲酸甲酯
参考文献:钌催化的n-(2-吡啶基)酰胺与异丙醇和芳基硼酸酯的还原化
标题:钌催化的n-(2-吡啶基)酰胺与异丙醇和芳基硼酸酯的还原化
摘要:描述了一种新的酰胺与稳定反应物的三组分还原芳基化反应(iproh和芳基硼酸酯),利用2-吡啶基(py)导向基团.N-Py-酰胺底物可以很容易地由羧酸和pynh 2制备,所得的n-Py-1-芳基烷胺反应产物很容易通过用hcl取代hn-Py基团而转化为相应的氯化物.1-芳基-1-氯代烷烃产品可进行取代和交叉偶联反应.因此,获得了将羧酸转化成各种官能团的通用方案.Py‐nh 2副产物可以回收利用.
Doi:10.1002/anie.201810947
海关参考信息
- 2912110000-甲醛
2915110000-甲酸
2933310010-吡啶
2909199090-其他醚及其衍生物 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
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专利信息
专利号:US-11744150-B2
优先权日:2012-01-20
标 题:Synthesis of aza-acenes as novel n-type materials for organic electronics
发明人:THOMPSON MARK E; SOMMER JONATHAN R; BARTYNSKI ANDREW
权利人:UNIV SOUTHERN CALIFORNIA
摘要:Acenes, such as aza-acenes are attractive materials for organic semiconductors, specifically for n-type materials. There are disclosed new derivatives of acenes that are fabricated using novel synthesis. For example, the disclosed fabrication strategies have allowed for the first time new aza-tetracene and aza-pentacene derivatives. The HOMO and LUMO energy levels of these materials are tunable through appropriate substitution and as predicted, deepened. There are also disclosed organic photosensitive devices comprising at least one aza-acene such as aza-tetracene and aza-pentacene.
专利号:WO-2023081730-A1
优先权日:2021-11-03
标 题:4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
发明人:ELZEIN ELFATIH; LIU JIWEN
权利人:TEON THERAPEUTICS INC
摘要:The present invention relates to 82 specific 4-hydroxy-2-oxo-1,2- dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid CB2 receptor modulators for the treatment of cancer, e.g. to 6-(4- fluorophenyl)-4-hydroxy-1-(2-(4-methylpiperazin-1-yl)ethyl)-2-oxo-N- (spiro[2.3]hexan-5-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (example 1, compound 1) The present description discloses the synthesis and characterisation of the 82 claimed compounds as well as biological assays thereof.
专利号:US-2021313517-A1
优先权日:2012-01-20
标题:Synthesis of aza-acenes as novel n-type materials for organic electronics
专利号:US-2013187136-A1
优先权日:2012-01-20
标 题 :Synthesis of aza-acenes as novel n-type materials for organic electronics
专利号:US-6410526-B1
优先权日:1999-06-02
标题 :αv integrin receptor antagonists
发明人:DUGGAN MARK E; HARTMAN GEORGE D; MEISSNER ROBERT S; PERKINS JAMES J
权利人:MERCK & CO INC
摘要:The present invention relates to novel nonanoic acid derivatives, their synthesis, and their use as alphav integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors alphavbeta3 and alphavbeta5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.
专利号:CN-113235116-B
优先权日:2021-05-12
标题 :A kind of electrochemical synthesis method of bromopyridine derivatives