CAS: 857891-82-8; Azido-Peg8-Amine

相似化合物

951671-92-4 1207714-69-9 1333154-77-0

上下游产品

26-Amino-3,6,9,12,15,18,21,24-Octaoxahexacosan-1-Ol 15332-95-3

Azido-Peg8-Nhboc置于盐酸体系中,用 1,4-二氧六环 作为反应溶剂,化学反应生成 26-叠氮基-3,6,9,12,15,18,21,24-八氧杂二十六烷-1-胺
参考文献:Cn116196434
标题:Cn116196434

专利信息

专利号:US-12037641-B2
优先权日:2015-11-20
标题:Modified nucleotide reagents
发明人：SHEN GENE; YUE STEPHEN; SEBO LUBOMIR; BROGLEY LOUIS
权利人:PACIFIC BIOSCIENCES CALIFORNIA INC
摘要:Labeled nucleotide analogs comprising at least one avidin protein, at least one dye-labeled compound, and at least one nucleotide compound are provided. The analogs are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The analogs are detectable with high sensitivity at desirable wavelengths. They contain structural components that modulate the interactions of the analogs with DNA polymerase, thus decreasing photodamage and improving the kinetic and other properties of the analogs in sequencing reactions. Also provided are nucleotide and dye-labeled compounds of the subject analogs, as well as intermediates useful in the preparation of the compounds and analogs. Compositions comprising the compounds, methods of synthesis of the intermediates, compounds, and analogs, and mutant DNA polymerases are also provided.

专利号:US-9957291-B2
优先权日:2013-08-05
标题 :Protected fluorescent reagent compounds
发明人：SEBO LUBOMIR; HANES JEREMIAH; SHEN GENE; BROGLEY LOUIS; YUE STEPHEN; ZHENG FRANK; LAPIN YURI; LYLE JOHN; OSUNA HONEY; FEDOROV ANDREI
权利人:PACIFIC BIOSCIENCES CALIFORNIA INC
摘要:Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.