7782-24-3 = 696-29-7 + 28523-32-2 + 103254-49-5 反应条件:1.1 Reagents: Hydrogen,Ammonia Catalysts: Aluminum Magnesium Oxide (Al2Mgo4),Ruthenium Tungsten Oxide Solvents: Cyclopentyl Methyl Ether; 6 Bar,Rt -> 200 °C; 6.5 H,50 Bar,200 °C 标题:One-Pot Reductive Amination Of Carboxylic Acids: A Sustainable Method For Primary Amine Synthesis 作者:Coeck,Robin; De Vos,Dirk E. 参考文献:Green Chemistry 日期:2020 卷标:22(15) 页码:5105-5114
📜3-异丙基苯酚置于氢气体系中,用 十二烷 作为反应溶剂,200.0 °C,2.0 Mpa 条件下,反应生成 异丙基环己烷 参考文献:将氧化还原活性金属位点限制在酸性多孔支架中,用于木质素衍生酚催化转化为环烷烃 标题:将氧化还原活性金属位点限制在酸性多孔支架中,用于木质素衍生酚催化转化为环烷烃 摘要:木质素衍生酚的加氢脱氧转化为可再生生物燃料的生产提供了一条有吸引力的途径;然而,恶劣的工艺条件严重阻碍了其实际应用.在此,我们报道了一种多孔金属硅酸盐(pms)材料pms-36,它由孔内的金属镍和路易斯酸al Iii位点组成,表现出在温和条件下催化愈创木酚加氢脱氧转化的高效性.pms-36 还表现出强大的稳定性,这可归因于受限孔内金属 Ni 和 Al Iii路易斯酸位点之间的强相互作用和电荷转移.这项研究表明了协同和限域效应在开发用于生物质及其衍生物化学转化的高性能且稳定的多相催化剂中的重要性. DOI:10.1039/d3Dt03002D
专利信息
专利号:US-6184168-B1 优先权日:1997-09-22 标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst 发明人:LYNCH THOMAS J 权利人:BRIDGESTONE CORP 摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.
专利号:WO-9517903-A1 优先权日:1993-12-28 标 题:Modular design and synthesis of oxazolone-derived molecules 发明人:HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG 摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.
专利号:US-2003162992-A1 优先权日:2001-12-14 标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides 发明人:WATANABE KYOICHI A; DU JINFA 摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-6800785-B1 优先权日:2002-10-15 标题:Process for the synthesis of estrogen receptor modulators 发明人:MENG DONGFANG 权利人:MERCK & CO INC 摘要:The present invention relates to processes for the synthesis of intermediates useful for the synthesis of estrogen receptor modulators. The process includes new methods for annelating 5-, 6- and 7-membered cycloalkenones onto an indanone.
专利号:US-7101526-B2 优先权日:2001-08-02 标 题:Catalyst and its use in the synthesis of hydrogen peroxide 发明人:PAPARATTO GIUSEPPE; DE ALBERTI GIORDANO; D ALOISIO RINO; BUZZONI ROBERTO 权利人:POLIMERI EUROPA SPA 摘要:The present invention relates to a catalyst consisting of: (a) one or more metals of the platinum group as active components; (b) one or more polyolefins; and (c) a carrier. The invention also relates to a process for the synthesis of hydrogen peroxide (H 2 O 2 ) from hydrogen and oxygen which uses said catalyst and the use of the hydrogen peroxide solution in oxidation processes catalyzed by titanium silicalite. The process operates under high safety conditions with a high productivity and molar selectivity towards the formation of H 2 O 2 .
专利号:US-10905769-B2 优先权日:2015-11-13 标 题:Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use 发明人:BURKE JR TERRENCE R; HYMEL DAVID T; TSUJI KOHEI 权利人:THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES 摘要:The description provides novel compounds that may serve as anticancer therapeutics. The compounds of the description bind to polo-like kinases through the polo-box domain. The peptide derivatives of the description have achieved improved efficacy in biochemical assays against Plk1. Exemplary compounds of the description include macrocyclic peptidomimetics with high affinity and selectivity for polo-like kinases, which may provide the basis for a new genre of anticancer therapeutics. Other exemplary compounds of the description include bi-valent compounds with that bind to polo-like kinases through both kinase domain and polo-box domain simultaneously by incorporating additional moieties that target Plk1 kinase domain, which significantly enhances affinitity relative and may provide the basis for a new genre of anticancer therapeutics. The description also provides methods of use, methods of preparation, compositions, and kits thereof. Further, the description provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.
摘要:Santana, V. C. S.; Munaretto, L. S.; de Lucca, E. C., Jr., Science of Synthesis Knowledge Updates, (2022) 1, 206. 摘要:Nolte, J. C.; Urlacher, V. B., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 53. 摘要:Dai, X.; Shi, F., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 128.