CAS: 6382-93-0; Z-D-Arg-Oh

该化合物是D-arginine 受保护的衍生物, 其特点是在α-氨基位置上有一个碳苯基(Cbz) 组, 这种改变加强了peptide合成的稳定性和选择性, 特别是用于手动或结构敏感应用. D 配置与 L-argin 相比, 具有明显的消毒性和酶性抗药性, 使得它对于研究peptide 相容和生物相互作用很有价值. Cbz 组在温和条件下促进受控的保护, 以确保与正方保护战略相兼容. 该组通常用于药用化学和生物化学研究, 以建造具有定制特性的含有Ricunine 的, 其高纯度和定义明确的立体化学学支持合成工作流程的可复制结果 .

结构式图片

相似化合物

113712-05-3 1119-34-2 114622-81-0

上下游产品

CAS号157-06-2 D-精氨酸 | CAS号501-53-1 氯甲酸苄酯

合成工艺路线路线简述

    📜D-精氨酸,氯甲酸苄酯置于sodium Hydroxide,碳酸氢钠体系中,用82%的收率获得产物n-α-羰基苯氧基-D-精氨酸
    参考文献:Fluorescence Studies On Nyctinasty Using Fluorescence Labeled Cis-P-Coumaroylagmatine,A Leaf-Opening Substance Of Albizzia Plants: Existence Of Genus-Specific Receptor For Leaf-Movement Factor
    标题:Fluorescence Studies On Nyctinasty Using Fluorescence Labeled Cis-P-Coumaroylagmatine,A Leaf-Opening Substance Of Albizzia Plants: Existence Of Genus-Specific Receptor For Leaf-Movement Factor
    摘要:We Developed Fluorescent Probes (1 And 2) Based On The Structure Of Cis-P-Coumaroylagmatine (3),A Leaf-Opening Substance Of Albizzia Julibrissim Durazz. These Probes Were Effective For The Leaf-Opening Of A. Julibrissin,And Specifically Bind To The Motor Cell Of This Plant. Moreover,Binding Of The Fluorescent Probe Was Specific To The Plant Motor Cell Contained In The Plants Belonging To The Albizzia Genus. These Results Showed That The Binding Of A Probe Compound With A Motor Cell Is Specific To The Plant Genus And Suggested That The Genus-Specific Receptor Molecule Cor The Leaf Movement Factor On A Motor Cell Would Be Involved In Nyctinasty. (C) 2003 Elsevier Science Ltd. All Rights Reserved.
    DOI:10.1016/s0040-4039(03)00376-9

    海关参考信息

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

    合成参考文献

    合成方法参考DOI号:10.1016/S0040-4039(03)00376-9
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