CAS: 624-72-6; 1,2-Difluoroethane

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CAS号6315-52-2 亚乙基二(p-甲苯磺酸盐) | CAS号383-50-6 对甲苯磺酸氟乙酯 | CAS号106-93-4 1,2-二溴乙烷 | CAS号107-21-1 乙二醇 | CAS号54509-73-8 ethene | CAS号624-73-7 1,2-二碘乙烷 | CAS号13709-36-9 二氟代氙 | CAS号107-06-2 1,2-二氯乙烷 | CAS号762-49-2 1-溴-2-氟乙烷 | CAS号371-62-0 2-氟乙醇 | CAS号75-73-0 四氟化碳 | CAS号354-33-6 五氟乙烷 | CAS号76-19-7 八氟丙烷 | CAS号359-35-3 1,1,2,2-四氟乙烷 | CAS号431-06-1 1,2-二氯-1,2-二氟乙烷... | CAS号354-15-4 1,2-二氟-1,1,2-三氯乙烷 | CAS号76-12-0 1,2-二氟四氯乙烷 | CAS号338-64-7 1-氯-1,2-二氟乙烷 | CAS号1842-05-3 1,1-二氯-1,2-二氟乙烷 | CAS号107-21-1 乙二醇

📜1,2-二碘乙烷置于mercury(II) Fluoride体系中,化学反应生成 1,2-二氟乙烷
参考文献:Iodine Excess And Hyperthyroidism
标题:Iodine Excess And Hyperthyroidism
摘要:150 Mug Iodine Are Daily Required For Thyroid Hormone Synthesis. The Thyroid Gland Has Intrinsic Mechanisms That Maintain Normal Thyroid Function Even In The Presence Of Iodine Excess. Large Quantities Of Iodide Are Present In Drugs,Antiseptics,Contrast Media And Food Preservatives. Iodine Induced Hyperthyroidism Is Frequently Observed In Patients Affected By Euthyroid Iodine Deficient Goiter When Suddenly Exposed To Excess Iodine. Possibly The Presence Of Autonomous Thyroid Function Permits The Synthesis And Release Of Excess Quantities Of Thyroid Hormones. The Presence Of Thyroid Autoimmunity In Patients Residing In Iodine-Insufficient Areas Who Develop Iodine-Induced Hyperthyroidism Has Not Been Unanimously Observed. In Iodine-Sufficient Areas,Iodine-Induced Hyperthyroidism Has Been Reported In Euthyroid Patients With Previous Thyroid Diseases. Euthyroid Patients Previously Treated With Antithyroid Drugs For Graves' Disease Are Prone To Develop Iodine-Induced Hyperthyroidism. As Well,Excess Iodine In Hyperthyroid Graves' Disease Patients May Reduce The Effectiveness Of The Antithyroid Drugs. occasionally Iodine-Induced Hyperthyroidism Has Been Observed In Euthyroid Patients With A Previous Episode Of Post-Partum Thyroiditis,Amiodarone Destructive Or Type Ii Thyrotoxicosis And Recombinant Interferon-Cu Induced Destructive Thyrotoxicosis. Amiodarone Administration May Induce Thyrotoxicosis. Two Mechanisms Are Responsible For This Condition. One Is Related To Excess Iodine Released From The Drug,Approximately 9 Mg Of Iodine Following A Daily Dose Of 300 Mg Amiodarone. This Condition Is An Iodine-Induced Thyrotoxicosis Or Type I Amiodarone-Induced Thyrotoxicosis. The Other Mechanism Is Due To The Amiodarone Molecule That Induces A Destruction Of The Thyroid Follicles With A Release Of Preformed Hormones. This Condition Is Called Amiodarone-Induced Destructive Thyrotoxicosis Or Type Ii Thyrotoxicosis. Patients Developing Type I Thyrotoxicosis In General Have Preexisting Nodular Goiter Whereas Those Developing Type Ii Thyrotoxicosis Have A Normal Thyroid Gland. The Latter Group Of Patients,After Recovering From The Destructive Process,May Develop Permanent Hypothyroidism As The Consequence Of Fibrosis Of The Gland.
DOI:10.1089/105072501300176453

专利信息

专利号:US-2008032964-A1
优先权日:2006-04-10
标题:Process for the synthesis of azetidinone
发明人：KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

专利号:US-2006167025-A1
优先权日:2004-12-22
标 题:Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs
发明人：BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
权利人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
摘要:The invention relates to tricyclic amino alcohols of general formula (I) n nmethod for synthesis of same and use of same as anti-inflammatory agents.

专利号:US-10918627-B2
优先权日:2016-05-11
标 题:Convergent and enantioselective total synthesis of Communesin analogs
发明人：MOVASSAGHI MOHAMMAD; LATHROP STEPHEN PAUL; POMPEO MATTHEW W; CHANG WEN-TAU TIMOTHY
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I): n nor a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R 1 -R 8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.

专利号:US-8128902-B2
优先权日:2011-04-12
标题:Method for the synthesis of anhydrous hydrogen halide and anhydrous carbon dioxide
发明人：TARANCON III GREGORIO
权利人:TARANCON III GREGORIO; MIDWEST REFRIGERANTS LLC
摘要:A method for the synthesis of anhydrous hydrogen halide fluids from organic halide fluids, such as perfluorocarbon fluids and refrigerant fluids, and anhydrous carbon dioxide for the environmentally safe disposition thereof.

专利号:US-8043574-B1
优先权日:2011-04-12
标 题:Apparatus for the synthesis of anhydrous hydrogen halide and anhydrous carbon dioxide
发明人：TARANCON III GREGORIO
权利人:MIDWEST REFRIGERANTS LLC
摘要:An apparatus for the synthesis of anhydrous hydrogen halide fluids from organic halide fluids, such as perfluorocarbon fluids and refrigerant fluids, and anhydrous carbon dioxide for the environmentally safe disposition thereof.

专利号:US-8084630-B2
优先权日:2007-05-31
标 题 :Process for the synthesis of ramelteon and its intermediates
发明人：KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; RAFILOVICH MICHAL; MOHA-LERMAN ELENA BEN; LIFSHITZ-LIRON REVITAL
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; RAFILOVICH MICHAL; MOHA-LERMAN ELENA BEN; LIFSHITZ-LIRON REVITAL; TEVA PHARMA
摘要:The present invention provides processes and intermediates for the synthesis of ramelteon.