专利号:EP-3567040-B1 优先权日:2013-06-24 标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:US-2008214386-A1 优先权日:2004-03-01 标题:Catalyst for Cyclic Carbonate Synthesis 发明人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 权利人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 摘要:Provided are a solid catalyst which gives a cyclic carbonate at a high yield and a high selectivity, which is stable and which may be readily separated after reaction; and a method of industrially advantageous, inexpensive and safe production of a cyclic carbonate by the use of the catalyst. The catalyst contains an inorganic solid substance having a surface modified with an ionic substance containing a Group 15 element; or contains an ionic substance containing a Group 15 element, and an inorganic solid substance. The modifying group for surface modification of an inorganic solid substance is an ionic substance containing a Group 15 element. The ionic substance containing a Group 15 element is at least one substance selected from organic phosphonium salts, organic ammonium salts, organic arsonium salts and organic antimonium salts.
专利号:EP-3567040-A1 优先权日:2013-06-24 标题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:US-11186570-B2 优先权日:2017-05-17 标题:Intermediate of eribulin and preparation method therefor 发明人:ZHANG FUYAO; LI HUOMING; ZHANG XINNING 权利人:SELECTION BIOSCIENCE LLC 摘要:Disclosed are an intermediate of Eribulin and a preparation method therefor. In particular, disclosed are compounds as represented by formula II, formula III and formula V and a preparation method therefor. Ar is C 1-10 alkyl substituted, alkyloxy substituted or unsubstituted aryl; R 1 and R 2 is an acetal protecting group or a thioacetal protecting group; R 3 is hydrogen or a hydroxyl protecting group; and X is halogen or a leaving group. The preparation method therefor has the advantages of mild reaction conditions, high selectivity, easy purification, low synthesis cost and the like, being suitable for large scale production.
专利号:US-6160181-A 优先权日:1998-09-01 标题 :Tetraene derivative and process for producing the same 发明人:SEKO SHINZO; KONYA NAOTO; TAKAHASHI TOSHIYA; FURUTANI ATSUSHI 权利人:SUMITOMO CHEMICAL CO 摘要:A tetraene derivative of the formula (1): ##STR1## wherein Ar represents an aryl group which may be optionally substituted with at least one substituent, and R 1 and R 2 are identical or different and represent a hydrogen atom, a lower alkyl group or a protective group of a hydroxyl group; synthesis methods therefor and synthesis methods using the same.
专利号:CN-115087647-A 优先权日:2018-12-07 标 题:For the preparation of 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl) ) ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine synthesis method
参考文献:10.1023/a:1003465528709 摘要:Zucchi F, Fonsati M, Trabanelli G. Corrosion and corrosion inhibition of nickel in HClO4 solutions using the EQCM technique. Journal of Applied Electrochemistry. 1999 Mar;29(3):347–53. doi: 10.1023/a:1003465528709. 参考文献:10.1023/a:1010584531292 摘要:Park D, Moon J, Jang H, Kim K. Addition of Carbon Dioxide to Glycidyl Methacrylate over Polymer-Supported Quaternary Ammonium Salt Catalysts. Reaction Kinetics, Mechanisms and Catalysis. 2001 Jan;72(1):83–92. doi: 10.1023/a:1010584531292.