CAS: 58-72-0; Triphenylethylene

该化合物其结构特征为三联苯基,由三组附于一个中央乙烯单元的苯基组成,在室内温度高时,对黄色晶晶体固态的浅色无色,以高熔点著称,该化合物在有机化学和材料科学中的作用值得注意,特别是在开发有机发光二极管(OLEDs)和作为荧光染色方面.三联苯乙烯表现出有趣的光物理特性,包括强荧光和能够进行可逆光异化,使其在各种应用中有用,包括传感器和开关.此外,该化合物具有疏水性,在正常条件下相对稳定,尽管可发生氧化作用.该化合物还有兴趣研究分子识别和超分子化学,因为它能够通过欧元的堆叠和其他非共价相互作用与其他分子相互作用.在处理三苯乙烯时,应当采取安全防范措施,正如处理许多有机化合物一样,以避免潜在的健康危害.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号530-48-3 1,1-二苯基乙烯 | CAS号591-50-4 碘苯 | CAS号292638-84-7 phenylene-ethylene | CAS号108-86-1 溴苯 | CAS号501-65-5 二苯乙炔 | CAS号71-43-2 苯 | CAS号4648-54-8 叠氮基三甲基硅烷 | CAS号4428-13-1 1,1,2-三苯基乙醇 | CAS号98-80-6 苯硼酸 | CAS号95061-46-4 (|R|)-(+)-1,1,2... | CAS号108998-83-0 S-三苯基乙二醇 | CAS号183849-26-5 (3R)-2,2,3-trip... | CAS号157556-88-2 (3S)-2,2,3-trip... | CAS号101-81-5 二苯甲烷 | CAS号33027-38-2 2-chloro-1,3-di... | CAS号1607-57-4 三苯基溴基乙烯 | CAS号91-01-0 二苯甲醇 | CAS号100-51-6 苯甲醇 | CAS号18084-97-4 三苯基氯乙烯

合成工艺路线路线简述

    📜Alpha-溴苯乙烯置于bis(η3-Allyl-μ-Chloropalladium(II)),Tedicyp,Potassium Carbonate体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 46.0H,反应生成 三苯乙烯
    参考文献:在四膦-钯催化剂存在下通过 Heck 乙烯基化或 Suzuki 交叉偶联反应合成多取代烯烃
    标题:在四膦-钯催化剂存在下通过 Heck 乙烯基化或 Suzuki 交叉偶联反应合成多取代烯烃
    摘要:通过使用 [pdcl(C3H5)]2/cis,Cis,Cis-1,2,3,4-四[(二苯基膦基)甲基]环戊烷作为催化剂,一系列乙烯基溴与芳基硼进行 Suzuki 交叉偶联产率非常好的酸.此外,该催化剂可以在低负载下使用,甚至用于空间位阻底物的反应.在该催化剂的介导下,二苯乙烯和 1,1-二苯基乙烯与芳基卤化物发生 Heck 反应,反应生成三芳基乙烯衍生物.(© Wiley-Vch Verlag Gmbh & Co. Kgaa,69451 Weinheim,Germany,2003)
    DOI:10.1002/ejoc.200390161

    海关参考信息

    专利信息


    专利号:US-7956011-B2
    优先权日:2005-05-04
    标题:Materials and methods for the photodirected synthesis of oligonucleotide arrays
    发明人:SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN
    权利人:CANCER RES INST ROYAL
    摘要:Materials and methods for photodirected synthesis of oligonucleotide arrays on a solid substrate by photodirected synthesis are disclosed which employ a film formed from (i) a photoacid generator that on photolysis generates acid that is capable of directly removing the protecting group of the linker molecules or oligonucleotides and (ii) a polymer substantially lacking electronegative heteroatoms that are capable of hydrogen bonding with photogenerated acid. Methods of synthesizing an oligomer arrays are also described that use a film that restricts diffusion of reactants and products on the substrate during synthesis of the array and which includes a precursor of a deprotecting reagent. The method involves removing one or more of the non-required products of the deprotection reaction from the reactive array elements at which they are produced during the reaction, in order to displace the deprotection reaction towards completion.

    专利号:WO-2023112055-A1
    优先权日:2021-12-15
    标 题 :New synthetic process design for the synthesis of carboxy tormifene and purity analysis to strengthen antidoping testing
    发明人:KUMAR GANGASANI JAGADEESH; PAWAR SACHIN DATTRAM; RADHAKRISHNANAND PULLAPANTHULA; MURTY UPADHYAYULA SURYANARAYANA; SAHU PURAN LAL; DUBEY SACHIN; SAHU KAPENDRA; UPADHYAY AWANISH; KUMAR PRAMOD
    权利人:DIRECTOR NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RES GUWAHATI NIPER G; DIRECTOR NAT DOPE TESTING LABORATORY NDTL
    摘要:The present invention relates to a process for preparing a compound of formula I: I. The compound of formula I is useful in anti-doping tests.

    专利号:US-10941243-B2
    优先权日:2016-10-13
    标 题 :Polymer poly (triphenylacrylonitrite) and synthesis thereof
    发明人:TANG BENZHONG; QIU ZIJIE
    权利人:UNIV HONG KONG SCI & TECH
    摘要:A method is directed to synthesis of poly(triphenylacrylonitrite)s (PTPANs) comprising polycoupling dibromoarenes, internal diynes, and potassium ferrocyanide, resulting in polycoupled dibromoarenes, internal diynes, and potassium ferrocyanide; and producing poly(triphenylacrylonitrite)s (PTPANs) by catalysis of the polycoupled dibromoarenes, internal diynes, and potassium ferrocyanide with palladium acetate and sodium bicarbonate, wherein the catalysis is allowed to proceed in dimethylacetamide under nitrogen at a prescribed temperature for a prescribed time. Further, poly(triphenylacrylonitrite)s (PTPANs) is a polymer and comprises a backbone structure of n nwherein x and y are integers;n nwherein each R is independently selected from the group consisting ofn n nandn nwherein each R′ is independently selected from the group consisting of

    专利号:US-5783577-A
    优先权日:1995-09-15
    标题 :Synthesis of quinazolinone libraries and derivatives thereof
    发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M
    权利人:TREGA BIOSCIENCES INC
    摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

    专利号:US-6538128-B1
    优先权日:1997-09-08
    标题:Detritylation solvents for nucleic acid synthesis
    发明人:ZHANG GUANGRONG; TANG JIN-YAN
    权利人:AVECIA BIOTECHNOLOGY INC
    摘要:The invention provides improved processes for oligonucleotide synthesis utilizing arenes as solvents for detritylation of oligonucleotides.

    专利号:US-7582653-B2
    优先权日:2003-03-31
    标 题 :Mercaptophenyl naphthyl methane compounds and synthesis thereof
    权利人:COUNCIL SCIENT IND RES
    摘要:Novel mercaptophenyl naphthyl methane compounds, their pharmaceutically acceptable salts and compositions comprised thereof are useful for the prevention or treatment of various medical indications associated with estrogen dependent diseases or syndromes related to osteoporosis, bone loss, bone formation, cardiovascular disorders, neurodegenerative disorders, menopausal disorders, physiological disorders, diabetes disorders, prostatic carcinoma, cancer of breast, cancer of uterus, cancer of the cervix and cancer of the colon, threatened or habitual abortion, obesity, ovarian development or function, post-partum lactation and depression.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Abderrahman B, Maximov PY, Curpan RF, Fanning SW, Hanspal JS, Fan P, Foulds CE, Chen Y, Malovannaya A, Jain A, Xiong R, Greene GL, Tonetti DA, Thatcher GRJ, Jordan VC. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 Jan;20(1):11-25. doi: 10.1158/1535-7163.MCT-20-0563. Epub 2020 Nov 11.
    2: Rani S, Paul K. Triphenylethylene analogues: Design, synthesis and evaluation of antitumor activity and topoisomerase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112775. doi: 10.1016/j.ejmech.2020.112775. Epub 2020 Aug 30. 98(4):364-381. doi: 10.1124/molpharm.120.000054. Epub 2020 Aug 12. Erratum in: Mol Pharmacol. 2020 Oct;98(4):528.
    4: Maximov PY, Abderrahman B, Hawsawi YM, Chen Y, Foulds CE, Jain A, Malovannaya A, Fan P, Curpan RF, Han R, Fanning SW, Broom BM, Quintana Rincon DM, Greenland JA, Greene GL, Jordan VC. The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Mol Pharmacol. 2020 Jul;98(1):24-37. doi: 10.1124/mol.120.119776. Epub 2020 May 3.

    合成参考文献


    摘要:Zaidlewicz, M.; Krzemiński, M. P.; Dzieleńdziak, A., Science of Synthesis, (2009) 48, 382.
    摘要:Wang, K.; Wang, J., Science of Synthesis, (2022) , 11.
    摘要:Matsumoto, K.; Katsuki, T.; Arends, I. W. C. E., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 105.
    摘要:Matsumoto, K.; Katsuki, T.; Arends, I. W. C. E., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 104.
    摘要:Wong, O. A.; Ramirez, T. A.; Shi, Y., Science of Synthesis: Asymmetric Organocatalysis, (2012) 1, 820.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知