专利号:US-5919969-A 优先权日:1996-06-05 标 题 :Synthesis of yellow couplers 发明人:CRAWLEY MICHAEL W 权利人:EASTMAN KODAK CO 摘要:The invention provides a method of synthesis of a image-dye forming coupler of formula (I) wherein X is a substituent linked to the coupler by an atom of oxygen, sulfur or nitrogen R1 is an alkyl or aryl group, R2 is a hydrogen atom or an alkyl group; R3 to R7 are the same or different and selected from a hydrogen atom and substituent groups; which method comprises the reaction of a compound of formula (II) wherein R and R1 are the same or different and are as defined above for R1 and X is as defined above with a compound of formula (III) wherein R2 to R7 are as defined above, in the presence of an inert organic solvent.
专利号:US-2003232952-A1 优先权日:2001-02-02 标题:Design and synthesis of instant - degradable plastics 发明人:ROSEN OREN 摘要:A novel class of instant degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics is developed by providing a new application advantage of incorporating latent, labile, dormant chemical bond nuclei such as disulfide and sulfenyl derivatives of the plastic compounds with latent nucleophilic properties. The special advantage of the instant degradable polymers over the existing biodegradable and other degradable polymer counterparts, is their engineering and design, which makes the kinetics of their degradation instant, and the chemical and physical properties of their by-products allows soluble dissolution into non-toxic aqueous solvent media, thus enabling a practical treatment of waste and avoiding bio-hazardous pollution of the environment. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent dormant solubility properties that are triggered upon mild chemical reaction, thus enabling cost effective and facile recycling of plastic refuge.
专利号:US-2018361327-A1 优先权日:2016-02-26 标题 :Gas separation membrane, gas separation module, gas separator, gas separation method, composition for forming gas separation layer, method of producing gas separation membrane, polyimide compound, and diamine monomer 发明人:KODAMA KEISUKE; SAWADA MAKOTO; WADA KENJI 权利人:FUJIFILM CORP 摘要:A gas separation membrane including a gas separation layer contains a crosslinked polyimide compound. In the gas separation membrane, and a gas separation module, a gas separator, and a gas separation method obtained by using the gas separation membrane, the crosslinked polyimide compound has a specific structural portion. A composition for forming a gas separation layer suitable for forming a gas separation layer of the gas separation membrane; a method of producing a gas separation membrane obtained by using this composition; a polyimide compound suitable as a raw material of a gas separation layer of the gas separation membrane; and a diamine monomer suitable for synthesis of this polyimide compound are provided.
专利号:US-10906895-B2 优先权日:2017-02-16 标 题:Processes for the preparation of benzodiazepine derivatives 发明人:KIM IN JONG; YU JIANMING; BLAISDELL THOMAS P; Panarese Joseph; SHOOK BRIAN C; OR YAT SUN 权利人:ENANTA PHARM INC 摘要:The present invention relates to processes and intermediates useful in the preparation of biologically active molecules, especially in the synthesis of Respiratory Syncytial Virus (RSV) inhibitors. The present invention also relates to processes and intermediates for the preparation of compounds of formula (I): n n n n n n n n n n In particular, the present invention also relates to processes and intermediates for the preparation of compound I-a:
专利号:US-5663342-A 优先权日:1994-03-08 标 题 :2-chloro and 2-bromo derivatives of 1,5-iminosugars 发明人:BARTA THOMAS E; MUELLER RICHARD A 权利人:SEARLE & CO 摘要:Novel 2-chloro and 2-bromo derivatives of 1,5-iminosugars are disclosed, especially such derivatives of 1,5-dideoxy-1,5-imino-D-glucitol. These compounds are useful inhibitors of glucosidase enzymes and also are useful as antiviral agents and as intermediates for the synthesis of other enzyme inhibitors and antiviral compounds.
专利号:US-4463179-A 优先权日:1980-09-02 标题 :1H-1,2,3-triazol-5-ylthio ester of N-carbobenzyloxy-p-hydroxyphenylglycine 发明人:MURAKAMI MASAHIRO; KOBAYASHI MASATERU; YAMAMOTO KIMIYO; SHIBUYA CHISEI 权利人:ASAHI CHEMICAL IND 摘要:Novel thioesters effective as acylating agents for amines or hydrazines, especially effective as active esters in synthesis of cephalosporin compounds are disclosed. The novel thioester of the present invention can be prepared by reacting a thiol or a derivative thereof with an acetic acid derivative or a reactive derivative thereof. By reacting the thioester of the present invention with a 7-aminocephalosporin derivative or a salt thereof, cephalosporin derivatives or pharmacologically acceptable salts thereof which are excellent antibiotic substances having a high antimicrobial activity can be obtained in high yield very safely.