CAS: 2199-93-1; 3-Acetyl-6-Bromo-2H-Chromen-2-One

上下游产品

CAS号141-97-9 乙酰乙酸乙酯 | CAS号1761-61-1 5-溴水杨醛 | CAS号105-45-3 乙酰乙酸甲酯 | CAS号22532-62-3 4-溴-2-羟基苯甲醛 | CAS号626-34-6 3-氨基巴豆酸乙酯 | CAS号89-55-4 5-溴水杨酸 | CAS号106578-01-2 6-bromo-3-(2-br... | CAS号38486-11-2 (6E)-4-bromo-6-...

📜3-Acetyl-6-Bromo-4-Chlorochromen-2-One置于copper(L) Iodide,Potassium Carbonate,异丙醇体系中,化学反应 12.0H,以84%的收率获得3-乙酰基-6-溴香豆素
参考文献:异丙醇中cui对芳香族α-和β-卤代羰基化合物的区域选择性加氢脱卤
标题:异丙醇中cui对芳香族α-和β-卤代羰基化合物的区域选择性加氢脱卤
摘要:在碱性条件下,使用cui在异丙醇中开发了一种有效的且对区域选择性的芳香族α-和β-卤代羰基化合物进行加氢脱卤的方法.该反应体系可有效还原氯,溴和碘基团,并以羰基化合物形式提供高收率(最高97%).该方法是环境友好的,并且显示出对多种电子富和取代基的优异耐受性.
Doi:10.1002/ejoc.201801385

专利信息

专利号:US-2005170281-A1
优先权日:2002-06-21
标题:Method of cleaving labile functional groups from chemical compounds
发明人：STENGELE KLAUS-PETER
摘要:The present invention provides a method of cleaving labile functional groups from molecules by exposure to electromagnetic radiation in which the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group and are then exposed to electromagnetic radiation, with the labile functional group and the suitable chemical compound having different absorption maxima for electromagnetic radiation. Further, the invention provides a method of manufacturing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates. In addition, the present invention provides a chemical composition comprising a molecule with a labile functional group and a chemical compound whose triplet state is higher than the triplet state of the labile functional group, with the labile functional group and the chemical compound having different absorption maxima for electromagnetic radiation, and describes the use of the chemical composition in the manufacture of DNA chips.

专利号:WO-2004089529-A1
优先权日:2003-04-07
标 题:Method for the intramolecular energy transfer for the cleavage of labile functional group from biomolecules and the protected biomolecules
发明人：STEINER ULRICH; WOELL DOMINIK
权利人:STEINER ULRICH; UNIV KONSTANZ; WOELL DOMINIK
摘要:The present invention provides a chemical compound and a method for the cleavage of labile functional groups from molecules by the interaction of electromagnetic radiation by the use of the chemical compound. Further, the invention provides a method for the manufacture of DNA chips by spatially addressed light directed nucleotide synthesis on solid substrates. The cleavage of the labile functional group is achieved by intramolecular energy transfer of the excitation energy.

专利号:US-7598019-B2
优先权日:2002-03-04
标 题:Method for cleavage of labile functional groups from chemical compounds
发明人：STEINER ULRICH; WOLL DOMINIK; WALBERT STEFAN
权利人:UNI KONSTANZ
摘要:The present invention provides a method for cleavage of labile functional groups from molecules by the action of electromagnetic radiation, wherein the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group, and are subsequently exposed to electromagnetic radiation. Further, the invention provides a method for preparing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates, said method comprising the following steps: a) reacting the unprotected terminal 3′ or 5′ hydroxy group of a nucleoside and/or of a nucleotide arranged on the solid substrate under usual conditions with a photolabile protective group and optionally purifying the reaction product, b) applying a solution, suspension or dispersion of a chemical compound, whose triplet state is energetically higher than the triplet state of the photolabile protective group, to the surface of the carrier, said surface comprising the nucleotides and/or nucleosides modified in step a): c) irradiating, in a spatially selective manner, the surface of the carrier treated in step b) with electromagnetic radiation in the UV/VIS range with simultaneous, spatially selective release of a reactive OH group and subsequently reacting it with a nucleoside and/or nucleotide comprising a 5′ or 3′OH group, said nucleoside and/or nucleotide being further provided with a photolabile functional group. Moreover, the present invention provides a chemical composition comprising a molecule having a labile functional group, as well as a chemical compound whose triplet state is higher than the triplet state of the labile functional group, and it describes the use of the chemical composition for preparing DNA chips.