专利号:WO-2017072796-A1 优先权日:2015-10-30 标题 :2-pyridone based compounds useful as potential phosphodiesterase3a (pde3a)inhibitors and a process for the preparation thereof 发明人:KUMAR G JAGADEESH; MAHENDAR B; SAIDULU M; BANERJEE S K; RAO V JAYATHIRTHA 权利人:COUNCIL SCIENT IND RES 摘要:Formula A wherein X = COOCH 3 , COOC 2 H 5 , CN Y = Methyl, Phenyl R = alkyl, substituted phenyl, napthyl, furonyl, thiophenyl, substituted quinolinyl The present invention related to compounds of general FormulaA. The invention provides the synthesis of 2-pyridones useful as potential cardio tonic agents and a process for the preparation thereof.
专利号:US-5736123-A 优先权日:1990-08-09 标 题 :Cocaine receptor binding ligands 发明人:CARROLL FRANK I 权利人:RES TRIANGLE INST 摘要:Novel compounds useful as intermediates in the synthesis of compounds having high affinity for specific cocaine receptors in the brain have the formula ##STR1## wherein R is (CH 2 ) n CH 2 Y, and wherein Y is H or F, X is a pharmaceutically acceptable anion, and n wherein Sn (R 1 , R 2 , R 3 ) is ortho, meta or para and wherein R 1 , R 2 , R 3 are independently alkyl of 1-6 carbon atoms and n is an integer of 0-5.
专利号:EP-3210987-A1 优先权日:2007-08-06 标 题:Process for the synthesis of proteasome inhibitors
参考标题:Concise Synthesis Of The Antidepressive Drug Candidate Gsk1360707 By A Highly Enantioselective Gold‐catalyzed Enyne Cycloisomerization Reaction 作者:Henrik Teller,Alois Fürstner |发布日期:2011.7.4 摘要:Depressing Results Are Obtained From A Gold‐catalyzed Enyne Cycloisomerization Controlled By Phosphoramidite Ligands With Taddol‐related But Acyclic Backbones (See Scheme; Cbz=benzyloxycarbonyl). The "Triple‐reuptake Inhibitor" Gsk1360707 Was Obtained In Excellent Yield And Optical Purity, Therefore Highlighting The Relevance Of Asymmetric Gold Catalysis For Practical Applications.
合成参考文献
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