CAS: 190906-91-3; Benzyl 2-Methyl-4-Oxo-3,4-Dihydropyridine-1(2H)-Carboxylate
该化合物是属于二丙烯衍生物一类的化学化合物,该物质一般呈现黄色到褐色色,其特点是独特的双环结构,包括一个与碳基和酯功能组结合的环,苯基集团的存在会加强其脂性,有可能影响其溶解性和再活性.该化合物可能展示生物活动,使其对药用化学感兴趣,特别是药物的开发.其分子结构表明它有可能在各种化学反应中应用,包括涉及核本类替代或循环过程.与许多有机化合物一样,处理应该谨慎,考虑避免接触或不良反应的安全议定书.可能需要进一步研究,以充分阐明其在各个领域的特性和潜在应用,包括药物开发和合成化学.
- 英文名称Benzyl 2-Methyl-4-Oxo-3,4-Dihydropyridine-1(2H)-Carboxylate
- 中文名称2-甲基-4-氧代-3,4-二氢吡啶-1(2H)-羧酸苄酯
- IUPAC名称benzyl 2-methyl-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate
- 其它别名Benzyl 3,4-Dihydro-2-Methyl-4-Oxopyridine-1(2H)-Carboxylate; Benzyl 2-Methyl-4-Oxo-3,4-Dihydropyridine-1(2H)-Carboxylate; 1(2H)-Pyridinecarboxylic Acid, 3,4-Dihydro-2-Methyl-4-Oxo-, Phenylmethyl Ester; 3,4-Dihydro-2-Methyl-4-Oxopyridine-1(2H)-Carboxylate; Benzyl2-Methyl-4-Oxo-2,3-Dihydropyridine-1-Carboxylate
- CAS编号190906-91-3
- MFCD编号:MFCD11975367
- 分子式:C14H15NO3分子量:245.28
- 产品CID: 965786
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
185847-84-1 362704-44-7 919366-32-8物理性质
MSDS等安全信息
上下游产品
4-methoxypyridine methylmagnesium bromide benzyl chloroformate methylmagnesium chlorideH-pyridine-1-carboxylic acid benzyl ester3-(hydroxy-pyridin-4-yl-methyl)-2-methyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester H-pyridine-1-carboxylic acid benzyl ester3-[(2-chloro-phenyl)-hydroxy-methyl]-2-methyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester H-pyridine-1-carboxylic acid benzyl ester3-(hydroxy-phenyl-methyl)-2-methyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester H-pyridine-1-carboxylic acid benzyl ester3-(1-hydroxy-butyl)-2-methyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester合成工艺路线路线简述
📜在 盐酸,水体系中,用 乙醚 用作溶剂,以4.12 G的收率获得3,4-二氢-2-甲基-4-氧代吡啶-1(2H)-甲酸苄酯
参考文献:Stereoselective Synthesis Of 4-Amino-2,3-Unsaturated-N-Cbz-Imino-O-Glycosides Via New Diastereoisomeric N-Cbz-Imino Glycal-Derived Allyl N-Nosyl Aziridines
标题:Stereoselective Synthesis Of 4-Amino-2,3-Unsaturated-N-Cbz-Imino-O-Glycosides Via New Diastereoisomeric N-Cbz-Imino Glycal-Derived Allyl N-Nosyl Aziridines
摘要:The Glycosylation Of Alcohols By The New Diastereoisomeric D,L-6-Deoxy-N-Cbz-Imino Glycal-Derived Allyl N-Nosyl Aziridines 5 And 6 Affords,After Deprotection Of The 4-(N-Nosylamino) Group,The Corresponding 2,3-Unsaturated-N-Cbz-Imino-O-Glycosides Bearing A Free Amino Group On C(4) Through A Completely 1,4-Regio-And Substrate-Dependent Stereoselective Glycosylation Process.
Doi:10.1021/ol900742P
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902300000-甲苯
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2012172449-A1
优先权日:2011-06-13
标题:Lactams as beta secretase inhibitors
发明人：BRODNEY MICHAEL AARON
权利人:PFIZER; BRODNEY MICHAEL AARON
摘要:Compound and pharmaceutically acceptable salts of the compound are disclosed, wherein the compound has the structure (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. The compound of formula I is useful as beta secretase inhibitor for use in the treatment of Alzheimer's and other neurodegenerative and/or neurological disorders.
