CAS: 15715-58-9; Triethylammonium Bicarbonatebuffer (1.0M Ph 8.5)

相似化合物

5204-74-0 17351-61-0 94527-74-9

上下游产品

CAS号121-44-8 三乙胺 | CAS号124-38-9 二氧化碳 | CAS号33962-65-1 AMP triethylamm... | CAS号58-61-7 腺苷 | CAS号2621-78-5 N-苄基氨基甲酸乙酯 | CAS号1466-67-7 1,3-二苄基脲 | CAS号5817-70-9 苄基氨基甲酸甲酯 | CAS号1467-21-6 Urea,N-phenyl-N...

📜三乙胺置于二氧化碳,水体系中,化学反应生成三乙基碳酸氢铵缓冲液
参考文献:Wo2007/107598
标题:Wo2007/107598

专利信息

专利号:US-12012427-B2
优先权日:2019-10-31
标 题 :Synthesis of Fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer
发明人：SINHA SURAJIT; KUNDU JAYANTA; GHOSH UJJWAL
权利人:INDIAN ASS FOR THE CULTIVATION OF SCIENCE
摘要:Present invention relates to stable Fmoc protected Morpholino monomers and corresponding oligonucleotides (PMO) and efficient synthesis of the same involving chlorophosphoramidate and H-Phosphonate chemistry. Successful syntheses of the oligonucleotide with higher yield and lesser time have been accomplished employing solid phase synthesis and easy deprotection of Fmoc group with Piperidine.

专利号:US-7786296-B2
优先权日:2004-02-25
标题:Silyl linker for solid-phase synthesis of nucleic acid
发明人：SEKINE MITSUO; SEIO KOHJI; OHKUBO AKIHIRO
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:The purpose of the invention is to develop a silyl linker that can be efficiently introduced on a solid-phase support used for the synthesis of nucleic acid oligomers such as DNA. The present invention relates to a silyl linker for use in the solid-phase synthesis of nucleic acid, comprised of a compound of the general formula or its ester or salt:n nH—(R1)Si(R2)-(C 6 H 4 )—CONH-(A)-COOH  (I)n nwherein each of R1 and R2 is an alkyl or aryl group, and (A) represents a spacer moiety; a 3′-end nucleoside unit having said compound linked via an oxygen atom to the 3-position of a sugar of the nucleoside or its derivative, a solid-phase support having the 3′-end nucleoside unit, and a method for synthesis of nucleic acid oligomer with the use of said solid-phase support.

专利号:US-6048975-A
优先权日:1991-09-12
标 题:Process for the chemical synthesis of oligonucleotides
发明人：PFLEIDERER WOLFGANG; BERGMANN FRANK
权利人:HOECHST AG
摘要:A process for the chemical synthesis of oligonucleotides n Use of a dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group in the chemical synthesis of DNA and RNA and suitable synthetic processes. n The ease of detection of the dansyl protective group and the ease of elimination from the sugar residue of the nucleotide without side reactions make oligonucleotide synthesis possible with high yields in very small quantities.

专利号:US-12281135-B2
优先权日:2019-07-25
标 题 :Synthesis of 6-azido-6-deoxy-2-n-acetyl-hexosamine-nucleoside diphosphate
发明人：HOOGENBOOM JORIN; WIJDEVEN MARIA ANTONIA; VERKADE JORGE MERIJN MATHIEU; VAN DELFT FLORIS LOUIS; VAN BERKEL SANDER SEBASTIAAN
权利人:SYNAFFIX BV
摘要:The current invention concerns methods for the synthesis of 6-azido-6-deoxy-2-N-acetyl-monosaccharide-nucleoside diphosphate, in particular 6-azido-6-deoxy-2-N-acetyl-D-galactosamine-nucleoside diphosphate or 6-azido-6-deoxy-2-N-acetyl-D-glucosamine-nucleoside diphosphate. The synthesis method according to the invention is characterized by being highly efficient and high yielding. Also part of the present invention are key intermediates of this process.

专利号:US-5750380-A
优先权日:1981-06-30
标 题:DNA polymerase mediated synthesis of double stranded nucleic acids
发明人：ITAKURA KEIICHI; ROSSI JOHN J
权利人:CITY OF HOPE RESEARCH INST
摘要:A first polynucleotide is formed with a first particular sequence of nucleotides such as by providing a solid-phase support and adding nucleotides to the support. A second polynucleotide is formed in a similar manner with a second particular sequence of nucleotides which are complementary to the nucleotides in the first polynucleotide at first particular ends of the polynucleotides. The first particular ends may be the 3'-ends of the polynucleotides. The polynucleotides are hybridized or annealed at their 3'-ends to form a base-pair complementary stretch between the first and second polynucleotides. A repair synthesis is then provided in the first and second polynucleotides at second ends (such as the 5'-ends) opposite the first particular ends to provide a double-stranded polynucleotide. The repair synthesis may be monitored by labelling the second end (or 5'-end) of one or both of the nucleotides with radioactivity and then subjecting the nucleotides to an enzymatic reaction.

专利号:US-5945524-A
优先权日:1990-09-14
标 题 :Process for the chemical synthesis of oligonucleotides
发明人：PFLEIDERER WOLFGANG; BERGMANN FRANK
权利人:HOECHST AG
摘要:Use of a dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group in the chemical synthesis of DNA and RNA and suitable synthetic processes. n The ease of detection of the dansyl protective group and the ease of elimination from the sugar residue of the nucleotide without side reactions make oligonucleotide synthesis possible with high yields in very small quantities.