CAS: 134364-69-5; 2,3-Difluoroanisole

相似化合物

261763-29-5 203245-16-3 2324-98-3

上下游产品

CAS号6418-38-8 2,3-二氟苯酚 | CAS号74-88-4 碘甲烷 | CAS号1489-53-8 1,2,3-三氟苯 | CAS号67-56-1 甲醇 | CAS号3862-73-5 2,3,4-三氟苯胺 | CAS号100-66-3 苯甲醚 | CAS号406482-22-2 4-溴-2,3-二氟苯甲醚 | CAS号256417-11-5 2,3-二氟-4-甲氧基苯甲醛

2,3-二氟苯酚,碘甲烷置于potassium Carbonate体系中,用 二甲基亚砜 用作溶剂,化学反应 0.5H,以78%的收率获得2,3-二氟苯甲醚
参考文献:康普他汀a-4氟化类似物的合成及其抗癌活性
标题:康普他汀a-4氟化类似物的合成及其抗癌活性
摘要:描述了一系列氟化苯甲醛的合成及其在wittig合成氟取代的斯蒂苯酯中的用途.3,5-二氟-4-羟基苯甲醛(6)和3-氟-4-甲氧基苯甲醛(11)是通过duff将3,5-二氟苯酚和2-氟苯甲醚甲酰化而制备的.通过friedel-Crafts用α,α-二氯甲基甲基醚将2,3-二氟茴香醚甲酰化,获得了2-甲氧基-3,4-二氟苯甲醛.所述醛用于制备一系列抗癌康普他汀a-1,A-2和a-4的氟化类似物.氟康他汀的体外抗癌特性已有报道.活性最高的氟类似物3-Deoxy-3-Fluoro-Combretastatin A-4(z-2)保留了ca-4的有效细胞生长抑制特性.
Doi:10.1016/s0022-1139(03)00117-9

专利信息

专利号:WO-2022256660-A1
优先权日:2021-06-04
标 题:Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels
发明人：HARRISON CRISTIAN
权利人:VERTEX PHARMA
摘要:Provided in this application is a process for making Compound I (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.

专利号:US-10424794-B2
优先权日:2014-07-02
标题:Ionic complex, electrolyte for nonaqueous electrolyte battery, nonaqueous electrolyte battery and ionic complex synthesis method
发明人：TAKAHASHI MIKIHIRO; MORINAKA TAKAYOSHI; SHINMEN MASUTAKA; YAMAMOTO KENTA; KAWABATA WATARU; KUBO MAKOTO; FUJIMOTO MASATAKA; MATSUZAKI HIROKI; TSUJIOKA SHOICHI
权利人:CENTRAL GLASS CO LTD
摘要:To provide a material suitable for a nonaqueous electrolyte battery having high-temperature durability. An ionic complex of the present invention is represented by any of the following formulae (1) to (3). For example, in the formula (1), A is a metal ion, a proton, or an onium ion; M is any of groups 13 to 15 elements. R 1 represents a C 1 to C 10 hydrocarbon group which may have a ring, a heteroatom, or a halogen atom, or —N(R 2 )—. R 2 at this time represents hydrogen atom, alkali metal atom, a C 1 to C 10 hydrocarbon group which may have a ring, a heteroatom, or a halogen atom. R 2 can also have a branched chain or a ring structure when the number of carbon atoms is 3 or more. Y is carbon atom or sulfur atom. a, o, n, p, q, and r are each predetermined integers.

专利号:US-11213031-B2
优先权日:2017-11-13
标 题:Tetrazolylpropyl derivatives and their use as fungicides
发明人：SUDAU ALEXANDER; HOFFMANN SEBASTIAN; DAHMEN PETER; WEBSTER ROBERT ALAN; MEISSNER RUTH; GOERTZ ANDREAS; MILLER RICARDA; COQUERON PIERRE-YVES; BERNIER DAVID; NICOLAS LIONEL; BRUNET STEPHANE; KENNEL PHILIPPE; TOQUIN VALERIE; GOURGUES MATHIEU; LOQUE DOMINIQUE; THOMAS VINCENT
权利人:BAYER AG; BAYER CROPSCIENCE AG
摘要:The present invention relates to tetrazolylpropyl derivatives of formula (I) n nwherein one of V 1 and V 2 represents CR 3 and the other one of V 1 and V 2 represents N, Q represents a 6-membered aromatic cycle as defined in the specification, and R 1 , R 2 , R 3 , R 4 , and R 5 are defined as disclosed in the specification, to compositions comprising such compounds, to the use of said compounds as fungicides, as well as to particular intermediates useful in the synthesis of said tetrazolylpropyl derivatives.

专利号:CN-1190093-A
优先权日:1998-03-04
标 题 :Synthesis of 4-methoxyl polyfluorophenyl nitrile

专利号:US-7294732-B2
优先权日:2002-08-07
标 题:Silicon compound
发明人：OHNO KOHJI; TSUJII YOSHINOBU; FUKUDA TAKESHI
权利人:CHISSO CORP
摘要:A silicon compound represented by Formula (1). In Formula (1), R 1 is a group independently selected respectively from the group consisting of a hydrogen atom, alkyl, substituted or non-substituted aryl and substituted or non-substituted arylalkyl, and A 1 is an organic group substituted with a halogenated sulfonyl group and is preferably a group represented by Formula (2). In Formula (2), X is halogen; R 2 is alkyl; a is an integer of 0 to 2; and Z 1 is a single bond or alkylene having a carbon number of 1 to 10. n n n n n n n n n n The silicon compound provided by the present invention is a silsesquioxane derivative having an excellent living polymerizable radical polymerization initiating function. For example, it is possible to commence polymerization by allowing an acryl base monomer to coexist to form an acryl base polymer making use of one point of the structure of the silsesquioxane in the present invention as a starting point. Because a halogenated sulfonyl group has a strong electrophilicity, it is possible to synthesize various silsesquioxane derivatives by reacting the silicon compound provided by the present invention with various nucleophilic reagents, and it can actively be used as an intermediate useful for organic synthesis.

专利号:CN-110922306-B
优先权日:2019-12-17
标 题:A kind of synthesis technology of 2,3-difluoro-4-alkoxyphenol