CAS: 106627-54-7; N-Hydroxysulfosuccinimide Sodium Salt

相似化合物

152305-87-8 76931-93-6 906564-59-8

专利信息

专利号:US-11466050-B2
优先权日:2014-09-29
标 题 :Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides
发明人：KNAUER SASCHA; ROESE TOBIAS MICHAEL LOUIS; AVRUTINA OLGA; KOLMAR HARALD; UTH CHRISTINA
权利人:SULFOTOOLS GMBH
摘要:The invention relates to a method for peptide synthesis, wherein said method comprises the steps of reacting a first amino acid or a first peptide with an α-amine protected second amino acid in a solvent selected from the group consisting of water, alcohol, and a mixture of water and alcohol, and removing the α-amine protecting group with a deprotecting solution. The invention further relates to protective agents, their use and an apparatus for carrying out a method for solid phase synthesis of peptides.

专利号:US-9549995-B2
优先权日:2012-03-26
标 题:Efficient synthesis of ethylenedicysteine-sugar conjugates for imaging and therapy
发明人：YANG DAVID J; YU DONG-FANG
权利人:UNIV TEXAS
摘要:Novel methods of synthesis of ethylenedicysteine-sugar conjugates and therapeutic and diagnostic applications of such conjugates are disclosed. Methods of synthesizing these conjugates in high purity are also presented as using starting materials such as thiazolidine carboxylic acid. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these conjugates prepared herein, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-9988388-B2
优先权日:2012-11-21
标 题:Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C- functionalized derivatives thereof
发明人：DENAT FRANCK; DESOGERE PAULINE; BERNHARD CLAIRE; ROUSSELIN YOANN; BOSCHETTI FREDERIC
权利人:UNIV BOURGOGNE; CENTRE NAT RECH SCIENT
摘要:A compound with formula (V′) n nthe synthesis method for compound (V′), and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I)n n nAlso, metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.

专利号:US-2025034610-A1
优先权日:2021-12-16
标题:Methods of polynucleotide synthesis
发明人：ESTRIN ERIC; PALLUK SEBASTIAN; ARLOW DANIEL
权利人:ANSA BIOTECHNOLOGIES INC
摘要:Disclosed herein are compositions and methods for de novo enzymatic synthesis of nucleic acid molecules. In particular, and among other things, compositions and methods of the present disclosure provide for reduction of non-terminations in a nucleic acid molecule product generated by de novo enzymatic synthesis. Compositions and methods of the present disclosure also include the use of a phosphatase enzyme to facilitate the reduction of non-terminations.

专利号:US-9006150-B2
优先权日:2004-11-08
标题:Structural nucleic acid guided chemical synthesis
发明人：HANSEN NILS JOKOB VEST; BLAKSKJAER PETER; HANSEN MARGIT HAAHR; PETERSEN LARS KOLSTER; HEITNER TARA RENEE
权利人:HANSEN NILS JOKOB VEST; BLAKSKJAER PETER; HANSEN MARGIT HAAHR; PETERSEN LARS KOLSTER; HEITNER TARA RENEE; VIPERGEN APS
摘要:Disclosed is a composition comprising the nucleic acid and a chemical compound, said composition forming a star structure defining 3 or more stems extending from a reaction center. The stems are formed by a nucleic acid duplex and the chemical compound has been formed in the reaction center as the reaction product of 3 or more chemical groups. The advantage of the composition is that a close proximity is provided between the chemical groups in the reaction center, thereby promoting a reaction. The invention also relates to a method for preparation of the composition. The advantage of the method is that it does not require the pre-synthesis of a large number of templates and that it is not dependent upon codon/anti-codon recognition for an encoded molecule to be formed.

专利号:US-9581601-B2
优先权日:2011-05-18
标题:Method of detection of amino acid sequence and/or identification of peptides and proteins, by use of a new derivatization reagent and synthesis of 5-formyl-benzene-1,3-disulphonic acid as derivatization reagent
发明人：CINDRIC MARIO; HAMERSAK ZDENKO; DODIG IVANA
权利人:CINDRIC MARIO; HAMERSAK ZDENKO; DODIG IVANA; RUDJER BOSKOVIC INST
摘要:Present invention refers to a novel and improved method of derivatization and detection of amino acid sequence and/or identification of proteins, peptides by a new derivatization compound. Precisely, the method discloses a novel approach to derivatization of peptides or proteins by compounds comprising two or more sulfonyl groups and analysis of derivatized analytes in negative mode of operation of mass spectrometer. This method allows unambiguous analysis of amino acid sequence of long-chain peptides/proteins. Also, the invention discloses a novel synthesis procedure of 5-formyl-benzene-1,3-disulphonic acid as derivatization compound.