McN-A-343
Chemical Name: 4-Hydroxy-N,N,N-trimethyl-2-butyn-1-ammonium 3-chlorophenylcarbamate
项目整合开发状态: Biological Testing
项目研究机构: Ortho-McNeil (Originator)
合成路线:The reaction of m-chlorophenyl isocyanate (I) with 4-chloro-2-butyn-1-ol (II) gives 4-chloro-2-butynyl-N-(3-chlorophenyl)carbamate (III),which is treated with trimethylamine in benzene.
📌 参考资料/链接：
参考文献标题:Ammoniumaliphatic esters of carbamic acids
文献作者:Hopkins,T.R.
参考来源:US 3100223
📄 详细内容
合成路线:The reaction of m-chlorophenyl isocyanate (I) with 4-chloro-2-butyn-1-ol (II) gives 4-chloro-2-butynyl-N-(3-chlorophenyl)carbamate (III),which is treated with trimethylamine in benzene.
参考文献标题:Unusual pressor agents: acetylenic carbamates
文献作者:Hopkins,T.R.; et al.
参考来源:J Org Chem 1962,27659-662
合成路线:The reaction of m-chlorophenyl isocyanate (I) with 4-chloro-2-butyn-1-ol (II) gives 4-chloro-2-butynyl-N-(3-chlorophenyl)carbamate (III),which is treated with trimethylamine in benzene.
参考文献标题:McN-A-343
文献作者:Casta馿r,J.; Blancafort,P.; Serradell,M.N.; Thorpe,P.J.
参考来源:Drugs Fut 1981,6(5),284