新产品编号:1718561
Chemical Name: 2-[4-[3-(4-Aminophenyl)ureido]benzamido]-4,5-dimethoxybenzoic acid ethyl ester
项目整合开发状态: Biological Testing
项目研究机构: Japan Energy (Originator)
合成路线:Treatment of substituted aminobenzoate (I) with 4-nitrobenzoyl chloride (II) affords amide (III),whose nitro group is converted into an amino group by hydrogenation over Pd/C,providing compound (IV).Finally,reaction of aniline (IV) with isocyanate (V) furnishes the target product.
📌 参考资料/链接:
参考文献标题:Synthesis and structure-activity relationship of inhibitor on smooth muscle cell proliferation induced by PDGF
文献作者:Hayashi,H.; Goto,Y.; Isobe,Y.; Misawa,S.; Ogita,H.; Sekine,R.; Takaku,H.
参考来源:19th Symp Med Chem (Nov 17 1999,Tokyo) 1999,Abst 1P-03