新产品编号:1715397
Chemical Name: 2-Amino-N-heptylacetohydroxamic acid
项目整合开发状态: Biological Testing
项目研究机构: Chiesi (Originator)
合成路线:Condensation of N-heptylhydroxylamine (I) with the protected glycine succinimidyl ester (II) produced the O-acyl intermediate (III),which spontaneously rearranged to the N-acyl analogue (IV).Then,cleavage of the amino protecting group of (IV) furnished the title N-hydroxy glycinamide.
📌 参考资料/链接：
参考文献标题:Synthesis of a new series of N-hydroxy,N-alkylamides of aminoacids as ligands of NMDA glycine site
文献作者:Pietra,C.; Delcanale,M.; Merlini,L.; Bergamaschi,M.; Ventura,P.; Servadio,V.; Villetti,G.; Redenti,E.; Ghidini,E.
参考来源:Eur J Med Chem 1999,34(9),711