ACPA

Chemical Name: (5Z,8Z,11Z,14Z)-N-Cyclopropyl-5,8,11,14-icosatetraenamide
项目整合开发状态: Preclinical
项目研究机构: Medical College of Wisconsin (Originator)
合成路线:Arachidonic acid (I) was converted to the mixed anhydride (II) upon treatment with isobutyl chloroformate and triethylamine.Subsequent condensation of (II) with 2-chloroethylamine (III) provided the target amide.

合成路线:Arachidonic acid (I) was converted to the mixed anhydride (II) upon treatment with isobutyl chloroformate and triethylamine.Subsequent condensation of (II) with cyclopropylamine (III) provided the target amide.