新产品编号:1603075

Chemical Name: 2-(4-Phenylbutyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-7-ol
项目整合开发状态: Biological Testing
项目研究机构: CoCensys (Originator)
合成路线:Treatment of 4-phenylbutanol (I) with PBr3 gave the corresponding bromide (II).6-Methoxytryptamine (III) was converted to the hydrochloride salt,and then condensed with formaldehyde under Pictet-Spengler conditions to furnish the pyridoindole system (IV).Alkylation of amine (IV) with bromide (II) then gave the phenylbutyl amine (V).Finally,O-demethylation of (V) employing BBr3 yielded the title compound.