新产品编号:1580927

Chemical Name: L-methionine adenosine-5'-O-yl ester trifluoroacetate
项目整合开发状态: Biological Testing
项目研究机构: ImaGene (Originator)
合成路线:Coupling of 2',3'-isopropylideneadenosine (I) with N-Boc-methionine (II) by means of DCC provided ester (III).Subsequent deprotection of (III) under acidic conditions yielded the title compound.

合成路线:The condensation between N-Boc-methionine (I) and O-(4-methoxybenzyl)hydroxylamine hydrochloride (II) gave the hydroxamate (III),which was then coupled with 2',3'-isopropylideneadenosine (IV) under Mitsunobu conditions to provide adduct (V).Subsequent deprotection with trifluoroacetic acid and anisole yielded the title compound.